Results 41 to 50 of about 1,110,939 (298)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The geobiological nitrogen cycle : from microbes to the mantle [PDF]

, 2017
Nitrogen forms an integral part of the main building blocks of life, including DNA, RNA, and proteins. N2 is the dominant gas in Earth’s atmosphere, and nitrogen is stored in all of Earth’s geological reservoirs, including the crust, the mantle, and the ...
Airapetian, Anbar, Barry, Beaumont, Bebout, Bebout, Bergin, Berner, Boyd, Boyd, Boyd, Boyd, Brandes, Busigny, Canfield, Canfield, Carlucci, Cartigny, Dalou, Dalsgaard, Dauphas, Fani, Farquhar, Farquhar, Fennel, Fischer, Frost, Garvin, Glass, Godfrey, Goldblatt, Goldschmidt, Gruber, Haendel, Halama, Halliday, Haqq-Misra, Harlow, Hilton, Javoy, Johnson, Johnston, Kasting, Kavanagh, Kelley, Kerrich, Kharecha, Krissansen-Totton, Lam, Li, Li, Marty, Marty, Marty, Marty, Marty, Mikhail, Mikhail, Mikhail, Mikhail, Navarro-Gonzalez, Nishizawa, Nishizawa, Palot, Palya, Poulton, Raymond, Reinhard, Sahoo, Sanchez-Baracaldo, Schroeder, Scott, Scott, Som, Som, Stüeken, Stüeken, Stüeken, Thomazo, Tyrrell, Watenphul, Watenphul, Weiss, Zerkle, Zerkle   +84 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Exploring NOy chemistry in levitated aqueous aerosol droplets [PDF]

, 2009
Chemistry of reactive nitrogen oxides, NOy, is crucial for our understanding of composition and properties of the Earth’s atmosphere. The proof-of-principle experiments demonstrated that we are able to study the atmospheric fate of nitrogen oxides ...
Hunt, O.R., King, M.D., Pfrang, Christian   +2 more
core  

Variations in the predicted spatial distribution of atmospheric nitrogen deposition and their impact on carbon uptake by terrestrial ecosystems [PDF]

, 1997
Widespread mobilization of nitrogen into the atmosphere from industry, agriculture, and biomass burning and its subsequent deposition have the potential to alleviate nitrogen limitation of productivity in terrestrial ecosystems, and may contribute to ...
Brasseur, Guy, Braswell, Rob, Dentener, Frank, Holland, Elisabeth A, Lamarque, Jean-Francois, Levy, H, II, Muller, Jean-Francois, Penner, Joyce E, Roelofs, Geert-Jan, Sulzman, James, Townsend, Alan R   +10 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Nitrogen fixation sustained productivity in the wake of the Palaeoproterozoic Great Oxygenation Event [PDF]

, 2018
The marine nitrogen cycle is dominated by redox-controlled biogeochemical processes and, therefore, is likely to have been revolutionised in response to Earth-surface oxygenation.
Algeo, Thomas J., Beukes, Nicolas J., Cui, Ying, Izon, Gareth, Junium, Christopher K., Luo, Genming, Ono, Shuhei, Summons, Roger E, Xie, Shucheng   +8 more
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Ecological Energetic Perspectives on Responses of Nitrogen-Transforming Chemolithoautotrophic Microbiota to Changes in the Marine Environment

Frontiers in Microbiology, 2017
Transformation and mobilization of bioessential elements in the biosphere, lithosphere, atmosphere, and hydrosphere constitute the Earth’s biogeochemical cycles, which are driven mainly by microorganisms through their energy and material metabolic ...
Hongyue Dang, Chen-Tung A. Chen
doaj   +1 more source

Nitrogen Cycle (1991) [PDF]

, 1991
"New/February 1991/10M.""Water Quality."" Focus area : nutrients and bacterial wastes.""Nitrogen in the environment.""Published by University Extension. University of Missouri-Columbia.
Buchholz, Daryl, Killpack, Scott
core