Nitroglycerin as a Hypotensive Drug during General Anesthesia [PDF]
Survey of Anesthesiology, 1978 Circulatory variables and arterial partial pressure for oxygen (PaO2) were compared in 91 anesthetized patients who received infusions of either nitroglycerin (TNG) or nitroprusside (SNP) to induce hypotension for the purpose of decreasing intraoperative blood loss.
N. R. Fahmy
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Repurposing Drugs in Oncology (ReDO)—nitroglycerin as an anti-cancer agent [PDF]
ecancermedicalscience, 2015 Nitroglycerin (NTG), a drug that has been in clinical use for more than a century, has a range of actions which make it of particular interest in an oncological setting. It is generally accepted that the main mechanism of action of NTG is via the production of nitric oxide (NO), which improves cardiac oxygenation via multiple mechanisms including ...
Sukhatme, Vidula +4 more
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Comparative Efficacies of Antimigraine Drugs Using Nitroglycerin Induced Migraine Rats Model
Journal of Pharmaceutical Research International, 2021 Aim: The migraine pathology is still not explained effectively. There is a common relationship between anxiety, depression, and migraine. So the aim of the study to illustrate effectively the behavioural and biomarker changes in the migraine condition. Methods: Nitroglycerin (NTG) induced migraine rats model was used the present study.
V. Parthasarathy, Anson S. Maroky
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Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application [PDF]
Cancer Science, 2009 Dose regimens of anticancer agents are usually designed on the basis of the maximum tolerable drug doses, and toxicity prevents drug usage at higher doses, even though the drugs may be more effective at the higher doses. We previously studied macromolecular anticancer drugs, i.e.
Takahiro, Seki +2 more
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Topical Nitroglycerin for Osteoporosis: Old Drug New Application
Journal of South Asian Federation of Obstetrics and Gynaecology, 2016 ABSTRACTOsteoporosis is a progressive bone disease characterized by a decrease in the bone mass and density, which can lead to an increased risk of fracture. Multiple treatments have been formulated for it like calcium, vitamin D supplements, bisphosphonates, raloxifene, hormone replacement therapies, teriparatide and calcitonin.
Ayush Agarwal +2 more
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Shear Stress Targeted Delivery of Nitroglycerin to Brain Collaterals Improves Ischaemic Stroke Outcome [PDF]
Advanced ScienceIn patients with ischaemic stroke, retrograde perfusion of the penumbra by leptomeningeal collateral vessels (LMCs) strongly predicts clinical outcome, suggesting that enhancing LMC flow can offer a novel therapeutic approach.
Magdalena Litman +21 more
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Sublingual and Buccal Delivery: A Historical and Scientific Prescriptive [PDF]
PharmaceuticsIn this review, our intention was to shed some light on the history of sublingual and buccal delivery over the past 75 years. By searching the query sublingual and buccal, we noticed four steady growth periods in the number of publications between 1950 ...
Sina Bahraminejad, Hassan Almoazen
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Nebulized nitroglycerin as an adjuvant drug in management of persistent pulmonary hypertension of newborns: a randomized controlled trial. [PDF]
Eur J PediatrFarag MM +3 more
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Trivial pursuit: which drug is in the syringe, nitroglycerin or epinephrine? [PDF]
Anaesthesia, 2001 Nian Chih Hwang
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Integrated ATAC-seq and RNA-seq analysis identifies Grid2 and Reln as potential regulatory genes in migraine pathophysiology [PDF]
The Journal of Headache and PainBackground Migraine pathophysiology involves epigenetic mechanisms, but key molecular regulators remain poorly defined. This study aimed to elucidate these mechanisms using a comprehensive multi-omics approach. Methods We established a nitroglycerin (NTG)
Fei Wang +4 more
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