Nitroglycerin as a Hypotensive Drug during General Anesthesia [PDF]
Survey of Anesthesiology, 1978 Circulatory variables and arterial partial pressure for oxygen (PaO2) were compared in 91 anesthetized patients who received infusions of either nitroglycerin (TNG) or nitroprusside (SNP) to induce hypotension for the purpose of decreasing intraoperative blood loss.
N. R. Fahmy
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Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application [PDF]
Cancer Science, 2009 Dose regimens of anticancer agents are usually designed on the basis of the maximum tolerable drug doses, and toxicity prevents drug usage at higher doses, even though the drugs may be more effective at the higher doses. We previously studied macromolecular anticancer drugs, i.e.
Takahiro Seki, Jun Fang, Hiroshi Maeda
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Repurposing Drugs in Oncology (ReDO)—nitroglycerin as an anti-cancer agent [PDF]
ecancermedicalscience, 2015 Nitroglycerin (NTG), a drug that has been in clinical use for more than a century, has a range of actions which make it of particular interest in an oncological setting. It is generally accepted that the main mechanism of action of NTG is via the production of nitric oxide (NO), which improves cardiac oxygenation via multiple mechanisms including ...
Vidula Sukhatme +4 more
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Discrepancies Between Nitroglycerin and NO-Releasing Drugs on Mitochondrial Oxygen Consumption, Vasoactivity, and the Release of NO [PDF]
Circulation Research, 2005 It has been generally acknowledged that the actions of glyceryl trinitrate (GTN) are a result of its bioconversion into NO. However, recent observations have thrown this idea into doubt, with many studies demonstrating that NO is present only when there are high concentrations of GTN.
Cristina Núñez +6 more
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Comparative Efficacies of Antimigraine Drugs Using Nitroglycerin Induced Migraine Rats Model
Journal of Pharmaceutical Research International, 2021 Aim: The migraine pathology is still not explained effectively. There is a common relationship between anxiety, depression, and migraine. So the aim of the study to illustrate effectively the behavioural and biomarker changes in the migraine condition. Methods: Nitroglycerin (NTG) induced migraine rats model was used the present study.
Anson S. Maroky, V. Parthasarathy
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Head-up tilt testing potentiated with oral nitroglycerin; a randomized trial of the contribution of a drug-free phase and a nitroglycerin phase in the diagnosis of neurally mediated syncope [PDF]
Europace, 1999 Since the pharmacological challenge with nitroglycerin (NTG) follows the initial drug-free phase in current tilt testing protocols, the effects of nitroglycerin alone and the appropriate duration of the basal phase are unknown.To optimize the test, a randomized intra-patient comparison of two protocols was undertaken: a conventional nitroglycerin test (
Angelo Bartoletti +9 more
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Two distinct stages and mechanisms of ST-elevation during cryothermal cavotricuspid isthmus ablation guided by intracardiac echocardiography: A case report. [PDF]
Indian Pacing Electrophysiol JRadiofrequency (RF) catheter ablation is the primary treatment for cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL), with cryothermal energy as an alternative.
Kasai Y, Iitsuka K, Morita J, Kitai T.
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Trivial pursuit: which drug is in the syringe, nitroglycerin or epinephrine? [PDF]
Anaesthesia, 2001 Nian Chih Hwang
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The mechanisms of nitroglycerin action: stenosis vasodilatation as a major component of the drug response. [PDF]
Circulation, 1981 The effect of sublingual or intracoronary nitroglycerin (NTG) on luminal caliber in normal and diseased portions of epicardial coronary arteries was determined in 85 lesions from 57 typical patients with ischemic heart disease. Measurements were made from coronary angiograms, using a computer-assisted method and a carefully blinded protocol for ...
B GBrown +4 more
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New CHF Drug Found Comparable with Nitroglycerin [PDF]
Emergency Medicine News, 2002 W. Richard Bukata
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