Results 91 to 100 of about 3,692,508 (293)
Topical nitroglycerin for management of peripheral extravasation of vasopressors: a case report
Oxford Medical Case Reports, 2020 Peripheral route for administration of vasopressors is often opted due to resource limitations or as a rescue until central venous access is established. This, however, is not devoid of complications, the most common being extravasation and tissue injury.
Ninadini Shrestha +5 more
semanticscholar +1 more source
Enhanced Drug Effect With Cutting Balloon Followed by Drug Coated Balloon in a Rabbit Model
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Drug‐coated balloon (DCB) are effective treatment options for patients with coronary artery disease and using of scoring or cutting balloon before the DCB usage were recommended. However, the effectiveness of lesion preparation with cutting balloons (CB) followed by DCB (CB + DCB) has not been evaluated before.
Manabu Shiozaki +9 more
wiley +1 more source
Vasodilator Therapy: Nitrates and Nicorandil. [PDF]
, 2016 Nitrates have been used to treat symptoms of chronic stable angina for over 135 years. These drugs are known to activate nitric oxide (NO)-cyclic guanosine-3',-5'-monophasphate (cGMP) signaling pathways underlying vascular smooth muscle cell relaxation ...
Kaski, JC, Tarkin, JM
core +1 more source
Drug prescription clusters in the UK Biobank: An assessment of drug-drug interactions and patient outcomes in a large patient cohort [PDF]
arXiv, 2022 In recent decades, there has been an increase in polypharmacy, the concurrent administration of multiple drugs per patient. Studies have shown that polypharmacy is linked to adverse patient outcomes and there is interest in elucidating the exact causes behind this observation.
arxiv
Clinical Pharmacology &Therapeutics, EarlyView.Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost +9 more
wiley +1 more source
Efficacy and disposal of drugs after the expiry date
The Egyptian Journal of Internal Medicine, 2019 Every drug manufacturer is legally bound to display the date of expiry on all pharmaceutical products. Excluding certain medicines such as nitroglycerin, insulin, epinephrine, and tetracycline, most medicines stored under reasonable conditions retain at ...
Gurmeet S Sarla
doaj +1 more source
Graph Distance Neural Networks for Predicting Multiple Drug Interactions [PDF]
arXiv, 2022 Since multidrug combination is widely applied, the accurate prediction of drug-drug interaction (DDI) is becoming more and more critical. In our method, we use graph to represent drug-drug interaction: nodes represent drug; edges represent drug-drug interactions.
arxiv
Drug-therapy networks and the predictions of novel drug targets [PDF]
Journal of Biology 2008, 7:20, 2008 Recently, a number of drug-therapy, disease, drug, and drug-target networks have been introduced. Here we suggest novel methods for network-based prediction of novel drug targets and for improvement of drug efficiency by analysing the effects of drugs on the robustness of cellular networks.
arxiv +1 more source
Comparison of diltiazem and nifedipine alone and in combination in patients with coronary artery spasm [PDF]
, 1987 Fifteen patients with coronary artery spasm completed a double-blind placebo-controlled trial comparing diltiazem and nifedipine. Increasingly, higher daily doses (diltiazem, 90 to 360 mg; nifedipine, 30 to 120 mg) were administered to achieve optimal ...
Feldman, Robert L. +5 more
core +1 more source
Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications
Mass Spectrometry Reviews, EarlyView.ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav +3 more
wiley +1 more source