Results 121 to 130 of about 3,692,508 (293)

UNSTABLE ANGINA TREATMENT IN VARIOUS PERIODS OF GEOMAGNETIC ACTIVITY

Odessa Astronomical Publications, 2014
In 145 patients with unstable angina (UA) there was analized an efficiency of a drug therapy at different types of heliogeophysical activity  (HA)  during the 23th solar cycle.  83 patients were examined at the period of a lower HA (Kp-index 16,19±0,18),
S. S. Parshina, L. K. Tokayeva, T. N. Afanas’yeva, S. N. Samsonov, V. D. Petrova, E. M. Dolgova, V. I. Manykina, E. S. Vodolagina   +7 more
doaj   +1 more source

Drug-drug interaction prediction based on co-medication patterns and graph matching [PDF]

arXiv, 2019
Background: The problem of predicting whether a drug combination of arbitrary orders is likely to induce adverse drug reactions is considered in this manuscript. Methods: Novel kernels over drug combinations of arbitrary orders are developed within support vector machines for the prediction.
arxiv  

Randomized trial to assess worsening renal function by adding dapagliflozin for acute decompensated heart failure

ESC Heart Failure, Volume 12, Issue 3, Page 2023-2033, June 2025.
Abstract Aims Dapagliflozin (DAPA), a sodium‐glucose co‐transporter 2 inhibitor, has been shown to reduce cardiovascular mortality among patients with chronic heart failure. We aimed to evaluate the impact on a worsening renal function (WRF) by adding DAPA as compared to standard decongestive therapy with loop diuretics alone.
Shodai Kawanami, Yasuyuki Egami, Masaru Abe, Mizuki Osuga, Hiroaki Nohara, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga‐Lee, Masamichi Yano, Masami Nishino   +11 more
wiley   +1 more source

Cesarean section with operation on placental support as an adapted EXIT procedure for fetal thyroid goiter: A case report and literature review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 2, Page 474-484, May 2025.
Abstract The ex‐utero intrapartum treatment (EXIT) procedure is a specialized delivery strategy that extends utero–placental–fetal circulation to convert a potential neonatal emergency condition into a condition that is compatible with postnatal life. Cesarean section with operation on placental support is an EXIT technique that requires a relatively ...
Sanpon Diawtipsukon, Woraluk Moradokkasem, Nareenun Chansriniyom, Pracha Nuntnarumit   +3 more
wiley   +1 more source

Aortic dissection in a patient treated with anlotinib for metastatic lung squamous cell carcinoma

Thoracic Cancer, 2020
Anlotinib is an anti‐angiogenic drug that targets vascular endothelial growth factor receptor, platelet‐derived growth factor receptor, fibroblast growth factor receptor, c‐Kit, and other kinases and has been approved for the treatment of advanced non ...
Bailing Jiang, Junhe Li, Jun Chen, Xiaojun Xiang, Jianping Xiong, Jun Deng   +5 more
doaj   +1 more source

Drug Recommendation toward Safe Polypharmacy [PDF]

arXiv, 2018
Adverse drug reactions (ADRs) induced from high-order drug-drug interactions (DDIs) due to polypharmacy represent a significant public health problem. In this paper, we formally formulate the to-avoid and safe (with respect to ADRs) drug recommendation problems when multiple drugs have been taken simultaneously.
arxiv  

Bench-to-bedside review : targeting antioxidants to mitochondria in sepsis [PDF]

, 2010
Peer reviewedPublisher ...
A Dhanasekaran, A Dyson, A Filipovska, AL Hill, AM James, B Bedogni, BE Minter, CA Macias, CC Chuang, CE Cross, D Brealey, D Brealey, D Brealey, D Graham, DA Lowes, DA Lowes, DP Jones, E Borrelli, ED Crouser, ED Crouser, F Arnalich, FN Gellerich, G Escames, G Escames, GF Kelso, GS Supinski, H Bayir, H Bohrer, H Zhang, HC Cowley, Helen F Galley, HF Galley, HF Galley, HF Galley, HF Goode, I Spasojević, I Vanhorebeek, J Ripcke, JC Marshall, JF Turrens, JJ Pandit, JV Esplugues, K Yassen, K Zhao, KS Roser, L Packer, M Qunitero, MD Wheeler, MD Wheeler, MP Fink, MP Fink, MP Murphy, MW Fariss, P Ghafourifar, P Wipf, RAJ Smith, RAJ Smith, RL Paterson, RO Poyton, S González-Rubio, S Rinaldi, SS Sheu, V Mishra, V Vanasco, VJ Adlam, VP Skulachev, W Droge, Z Lacza   +67 more
core   +2 more sources

Lactate orchestrates metabolic hemodynamic adaptations through a unique combination of venocontraction, artery relaxation, and positive inotropy

Acta Physiologica, Volume 241, Issue 5, May 2025.
Abstract Aim H+ facilitates metabolic blood flow regulation while negatively impacting cardiac contractility. Cardiovascular consequences of conjugate bases accumulating alongside H+ remain unclear. Here, we evaluate the cardiovascular effects of nine prominent carboxylates—particularly lactate, 3‐hydroxybutyrate, and butyrate—linked to metabolic and ...
Casper Homilius, Jacob M. Seefeldt, Jakob Hansen, Roni Nielsen, Frank V. de Paoli, Ebbe Boedtkjer   +5 more
wiley   +1 more source

On the Way to More Convenient Description of Drug-Plasma Protein Binding [PDF]

arXiv, 2012
The theoretical case is considered where the total amount of plasma protein is conserved, but the drug is eliminated after its single application. After a single drug application at time t = 0, the total drug concentration is measured at times ti,...,tk and the total drug concentration at time ti is denoted by {\phi}i.
arxiv  

Use of Fluid Gelatin in Lumbar Spinal Stenosis Undergoing Unilateral Biportal Endoscopic: A Prospective, Randomized Controlled Trial

Orthopaedic Surgery, Volume 17, Issue 5, Page 1340-1348, May 2025.
The 96 patients were randomly assigned to two groups: the Surgiflo Hemostatic Matrix (SHM) group and the non‐SHM group. The use of fluid gelatin effectively reduces intraoperative and postoperative bleeding without leading to additional complications.
Hao Yan, Mei Gao, Yu Zhang, Huaibin Wang, Yushan Zhu, Tiangang Zhou, Ruzhan Yao, Weiqiang Liu, Jesse Li‐Ling   +8 more
wiley   +1 more source