Results 141 to 150 of about 11,777 (217)
Influence of Formulating Factors on Drug Safety of Timed-Release Nitroglycerin Tablets
A peroral sandwich model tablet with timed release, containing proxyphylline and nitroglycerin, was developed. One layer of the tablet constituted the rapidly disintegrating and dissolving initial phase; the other, the depot phase, was in the form of an insoluble, indigestible skeleton.
W. A. Ritschel
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A New Topical Drug Delivery System for Nitroglycerin
Nitroglycerin has been the agent of choice for the treatment of angina pectoris for over 100 years. In recent years various long-acting preparations have been introduced for the prophylaxis of angina pectoris and most recently for use in the long term management of a patient with left ventricular dysfunction.
B. Pitt +7 more
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Antianginal drugs. Part II. Human pharmacology of nitroglycerin
Solomon Fisch
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New CHF Drug Found Comparable with Nitroglycerin
W. Richard Bukata
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The medical treatment of angina pectoris IV. Nitroglycerin as an antianginal drug
Wilbert S. Aronow
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The history of the discovery and development of drugs is replete with examples where chance and "serendipity" have resulted in important advances of knowledge. In the case of nitroglycerin it can be shown that what appears to have been a chance discovery was actually the result of a sequence of selective perceptions by, and cognitive processes in ...
R. Schüppel
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Homicide and nitroglycerin. A case of drug interaction
Journal of Chemical Education, 1972Examines the mysterious circumstances surrounding the death of a young woman in 1901 and the possibility that it was due to drinking nitroglycerin.
F J, Di Carlo, L C, Holmes
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Transdermal nitroglycerin prevents nonsteroidal anti-inflammatory drug gastropathy
European Journal of Pharmacology, 1995Abstract The application of a transdermal nitroglycerin patch (2–30 μg/3 h/rat) protected, in a dose-dependent manner, the rat gastric mucosa against damage induced by the nonsteroidal anti-inflammatory agent indomethacin (20 mg/kg s.c.).
M D, Barrachina +6 more
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Pulsed release of nitroglycerin from transdermal drug delivery systems
International Journal of Pharmaceutics, 1999To achieve a discontinuous drug delivery to the skin a new actively controlled transdermal system has been developed. The system consists of a tube shaped drug reservoir in combination with an electronic circuit and a gas producing cell. A magnetic switch was used to control the onset of the production of hydrogen gas.
R, Gröning, U, Kuhland
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Nitroglycerin: New concepts about an old drug
The American Journal of Medicine, 1976Abstract Increasing evidence has profoundly challenged previously accepted concepts about the actions and clinical uses of nitroglycerin. Traditionally, use of this agent has been contraindicated in patients with acute myocardial infarction because of its hypotensive effects, and it has had no place in the therapeutic armamentarium of heart failure or
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