Results 151 to 160 of about 11,777 (217)
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Assessment of the Drug Interaction between Intravenous Nitroglycerin and Heparin
Annals of Pharmacotherapy, 1992OBJECTIVE: To assess whether a clinically significant interaction occurs between heparin and nitroglycerin (NTG). METHODOLOGY: Activated partial thromboplastin time (APTT) was measured in patients with unstable angina who were stabilized on intravenous NTG and heparin just prior to weaning the NTG infusion, and one and four hours after stopping the NTG.
E R, Gonzalez +3 more
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Relief of coronary artery spasm by nitroglycerin: Time‐dependent variability in drug action
Catheterization and Cardiovascular Diagnosis, 1978AbstractThe arteriographic distinction between a fixed atheromatous obstruction and localized vasospasm in the coronary artery is often decided by the response of the lesion to nitroglycerin. We studied the time course of nitroglycerin in four patients with coronary artery spasm as revealed by selective angiography.
E L, Fallen +3 more
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Cardiovascular Drugs: From Nitroglycerin to Lipitor
2006Cardiovascular diseases are the leading cause of death worldwide and are projected to remain in the lead through 2025. Heart-related diseases include angina, arrhythmia, atrial fibrillation, congestive heart failure, hypertension, atherosclerosis, myocardial infarction (heart attack), and sudden cardiac death.
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Assessment of the Drug Interaction Between Alteplase and Nitroglycerin: An In Vitro Study
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2000Alteplase is the most commonly administered thrombolytic agent in the United States. However, concurrent therapy with nitroglycerin reduces plasma alteplase concentrations and its clinical efficacy. We sought to determine if this interaction is concentration and pH dependent. Seventy plasma samples were prepared and divided into three groups: alteplase
C M, White +4 more
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American Journal of Physiology-Legacy Content, 1957
The effects on respiratory rate and amplitude following intravenous injection of the vasodilator drugs, Urecholine (carbaminoyl-beta-methylcholine) and nitroglycerine were determined in dogs before and after bilateral vagotomy and isolation of the carotid sinuses.
R T, SCHOPP, T M, GILFOIL, W B, YOUMANS
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The effects on respiratory rate and amplitude following intravenous injection of the vasodilator drugs, Urecholine (carbaminoyl-beta-methylcholine) and nitroglycerine were determined in dogs before and after bilateral vagotomy and isolation of the carotid sinuses.
R T, SCHOPP, T M, GILFOIL, W B, YOUMANS
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Transdermal Absorption of Nitroglycerin from Microseal Drug Delivery (MDD) System
Angiology, 1983A recent important advance in biopharmaceutics has been the utilization of controlled delivery of drugs to the systemic circulation through the intact skin. With the conventional tablet and capsule dosage forms, the amount of drug absorbed through the gastrointestinal (GI) tract varies depending on the quan tity and types of food in the stomach, on ...
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Effect of intermittent exposure and drug-free intervals on the vascular tolerance to nitroglycerin
Life Sciences, 1989Recent reports suggest that intermittent nitroglycerin (NTG) treatment, incorporating a daily nitrate-free interval, can avoid the tolerance associated with continuous NTG therapy. This study has investigated whether an in vitro model of NTG tolerance could be used to examine the mechanisms of tolerance avoidance (by intermittent NTG exposure) and ...
E, Kowaluk, K, Hough, H L, Fung
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Drug corner: nitroglycerin ointment
Critical Care Nurse, 1981S, Burns-Stewart, S S, Stewart
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Nitroglycerin. The explosive drug
Journal of Chemical Education, 1971L C, Holmes, F J, Dicarlo
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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