Results 191 to 200 of about 3,729,717 (272)

Homicide and nitroglycerin: a case of drug interaction?

open access: closedJournal of Chemical Education, 1972
Examines the mysterious circumstances surrounding the death of a young woman in 1901 and the possibility that it was due to drinking nitroglycerin.
F. D. Di Carlo, L. C. Holmes
semanticscholar   +5 more sources

Influence of formulating factors on drug safety of timed-release nitroglycerin tablets.

open access: closedJournal of Pharmaceutical Sciences, 1971
A peroral sandwich model tablet with timed release, containing proxyphylline and nitroglycerin, was developed. One layer of the tablet constituted the rapidly disintegrating and dissolving initial phase; the other, the depot phase, was in the form of an ...
W. Ritschel
semanticscholar   +5 more sources

Nitroglycerin: new concepts about an old drug. [PDF]

open access: closedThe American Journal of Medicine, 1976
Abstract Increasing evidence has profoundly challenged previously accepted concepts about the actions and clinical uses of nitroglycerin. Traditionally, use of this agent has been contraindicated in patients with acute myocardial infarction because of its hypotensive effects, and it has had no place in the therapeutic armamentarium of heart failure or
R. Helfant
semanticscholar   +4 more sources
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Nitroglycerin ameliorates liver injury and regulates adaptive immunity in mice

Drug Development Research, 2020
This study aimed to assess the protective effect of nitroglycerin, a commonly used drug in cardiovascular diseases, on mice with acute liver injury induced by carbon tetrachloride (CCl4 ). The mice were randomly divided into three groups: control, CCl4 ,
Jian-he Gan, Zhong-hua Lu
exaly   +2 more sources

Absence of drug interaction between heparin and nitroglycerin. Randomized placebo-controlled crossover study.

Archives of Internal Medicine, 1990
The purpose of this randomized crossover study was to determine whether nitroglycerin interacts with heparin in terms of its anticoagulative properties as determined by activated partial thromboplastin time and thrombin time.
V. Bode   +3 more
semanticscholar   +4 more sources

Effect of intermittent exposure and drug-free intervals on the in vitro vascular tolerance to nitroglycerin.

open access: closedLife Sciences, 1989
Recent reports suggest that intermittent nitroglycerin (NTG) treatment, incorporating a daily nitrate-free interval, can avoid the tolerance associated with continuous NTG therapy. This study has investigated whether an in vitro model of NTG tolerance could be used to examine the mechanisms of tolerance avoidance (by intermittent NTG exposure) and ...
E. Kowaluk, K. Hough, H. Fung
semanticscholar   +5 more sources

Adhesive Matrix Type Transdermal Drug Delivery System for Nitroglycerin

Drug Development and Industrial Pharmacy, 1994
The kinetics of release of nitroglycerin from adhesive matrix type patches was studied. At a high drug to adhesive ratio the patch consisted of nitroglycerin in part dispersed as droplets in the adhesive and in part dissolved in the adhesive.
R. M. Pai   +3 more
semanticscholar   +3 more sources

Relief of coronary artery spasm by nitroglycerin: time-dependent variability in drug action.

Catheterization and Cardiovascular Diagnosis, 1978
The arteriographic distinction between a fixed atheromatous obstruction and localized vasospasm in the coronary artery is often decided by the response of the lesion to nitroglycerin.
E. Fallen   +3 more
semanticscholar   +4 more sources

Assessment of the Drug Interaction between Intravenous Nitroglycerin and Heparin

Annals of Pharmacotherapy, 1992
OBJECTIVE: To assess whether a clinically significant interaction occurs between heparin and nitroglycerin (NTG). METHODOLOGY: Activated partial thromboplastin time (APTT) was measured in patients with unstable angina who were stabilized on intravenous NTG and heparin just prior to weaning the NTG infusion, and one and four hours after stopping the NTG.
E. R. Gonzalez   +3 more
semanticscholar   +4 more sources

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