Results 211 to 220 of about 3,692,508 (293)

Nitroglycerin: New concepts about an old drug [PDF]

open access: closedThe American Journal of Medicine, 1976
Abstract Increasing evidence has profoundly challenged previously accepted concepts about the actions and clinical uses of nitroglycerin. Traditionally, use of this agent has been contraindicated in patients with acute myocardial infarction because of its hypotensive effects, and it has had no place in the therapeutic armamentarium of heart failure or
Richard H. Helfant
semanticscholar   +4 more sources

Homicide and nitroglycerin. A case of drug interaction

open access: closedJournal of Chemical Education, 1972
Examines the mysterious circumstances surrounding the death of a young woman in 1901 and the possibility that it was due to drinking nitroglycerin.
Frederick J. Di Carlo, Linda Culp Holmes
semanticscholar   +5 more sources

Influence of Formulating Factors on Drug Safety of Timed-Release Nitroglycerin Tablets

open access: closedJournal of Pharmaceutical Sciences, 1971
A peroral sandwich model tablet with timed release, containing proxyphylline and nitroglycerin, was developed. One layer of the tablet constituted the rapidly disintegrating and dissolving initial phase; the other, the depot phase, was in the form of an insoluble, indigestible skeleton.
W. A. Ritschel
semanticscholar   +5 more sources

Effect of intermittent exposure and drug-free intervals on the vascular tolerance to nitroglycerin

open access: closedLife Sciences, 1989
Recent reports suggest that intermittent nitroglycerin (NTG) treatment, incorporating a daily nitrate-free interval, can avoid the tolerance associated with continuous NTG therapy. This study has investigated whether an in vitro model of NTG tolerance could be used to examine the mechanisms of tolerance avoidance (by intermittent NTG exposure) and ...
Elizabeth A. Kowaluk   +2 more
semanticscholar   +5 more sources
Some of the next articles are maybe not open access.

Related searches:

Assessment of the Drug Interaction between Intravenous Nitroglycerin and Heparin

Annals of Pharmacotherapy, 1992
OBJECTIVE: To assess whether a clinically significant interaction occurs between heparin and nitroglycerin (NTG). METHODOLOGY: Activated partial thromboplastin time (APTT) was measured in patients with unstable angina who were stabilized on intravenous NTG and heparin just prior to weaning the NTG infusion, and one and four hours after stopping the NTG.
Susan Graham   +3 more
openaire   +4 more sources

Transdermal nitroglycerin as a step 3 antihypertensive drug

Clinical Pharmacology and Therapeutics, 1986
The antihypertensive effect of transdermal nitroglycerin was tested in 11 men with hypertension (mean age 60 years) whose diastolic blood pressure exceeded 90 mm Hg while receiving a diuretic and a beta-adrenergic blocker. In a double-blind, randomized crossover trial the subjects received weekly increments of placebo or nitroglycerin (5, 10, 20, and ...
Jay N. Cohn   +2 more
openaire   +4 more sources

Transdermal Absorption of Nitroglycerin from Microseal Drug Delivery (MDD) System

Angiology, 1983
A recent important advance in biopharmaceutics has been the utilization of controlled delivery of drugs to the systemic circulation through the intact skin. With the conventional tablet and capsule dosage forms, the amount of drug absorbed through the gastrointestinal (GI) tract varies depending on the quan tity and types of food in the stomach, on ...
A. Karim
openaire   +4 more sources

BIOEQUIVALENCE COMPARISON OF TWO DRUG-IN-ADHESIVE TRANSDERMAL NITROGLYCERIN PATCHES

American Journal of Therapeutics, 1996
Plasma concentrations of nitroglycerin, 1,2-dinitroglycerin and 1,3-dinitroglycerin in 50 healthy male subjects who received single 24-h applications of two 0.6 mg/h drug-in-adhesive transdermal nitroglycerin patch formulations were compared for the purpose of establishing bioequivalence.
Jeff M. Zumhofe   +7 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy