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Lysozyme and Human Serum Albumin Proteins as Potential Nitric Oxide Cardiovascular Drug Carriers: Theoretical and Experimental Investigation.

Journal of Physical Chemistry B, 2021
Nitric oxide-containing drugs present a critical remedy for cardiovascular diseases. Nitroglycerin (NG, O-NO) and S-nitrosoglutathione (SNG, S-NO) are the most common nitric oxide drugs for cardiovascular diseases. Insights regarding the binding affinity
C. Nassab   +5 more
semanticscholar   +1 more source

Liquid Chromatographic Method Development for Quantification of Inorganic Nitrite and Nitrate Impurities from Nitroglycerin Drug Substance by Using Ion-Pair Reagents with Liquid-Liquid Extraction Technique.

Journal of Chromatographic Science, 2019
A large number of laboratory studies have reported Nitrite (NO2-) and Nitrate (NO3-) to be among the most common degradation products of the high-explosive Nitroglycerin drug substance.
Pritesh Desai, P. Mehta, Avani Chokshi
semanticscholar   +1 more source

Transdermal Drug Delivery Systems (TDDS): Recent Advances and Failure Modes.

Molecular Pharmaceutics
Transdermal drug delivery systems (TDDS), commonly refered to as "patches", present a nonintrusive technique to provide medication without the need for invasive procedures.
Mohsen Ghaferi   +4 more
semanticscholar   +1 more source

Pulsed release of nitroglycerin from transdermal drug delivery systems

International Journal of Pharmaceutics, 1999
To achieve a discontinuous drug delivery to the skin a new actively controlled transdermal system has been developed. The system consists of a tube shaped drug reservoir in combination with an electronic circuit and a gas producing cell. A magnetic switch was used to control the onset of the production of hydrogen gas.
R. Gröning, U Kuhland
openaire   +3 more sources

Nitroglycerin ameliorates liver injury and regulates adaptive immunity in mice.

Drug development research (Print), 2020
This study aimed to assess the protective effect of nitroglycerin, a commonly used drug in cardiovascular diseases, on mice with acute liver injury induced by carbon tetrachloride (CCl4 ). The mice were randomly divided into three groups: control, CCl4 ,
Shuang Zhao   +5 more
semanticscholar   +1 more source

A New Topical Drug Delivery System for Nitroglycerin

1981
Nitroglycerin has been the agent of choice for the treatment of angina pectoris for over 100 years. In recent years various long-acting preparations have been introduced for the prophylaxis of angina pectoris and most recently for use in the long term management of a patient with left ventricular dysfunction.
J. Brymer   +7 more
openaire   +2 more sources

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