Results 21 to 30 of about 11,777 (217)

THE PROBLEM OF INTERCHANGEABILITY OF DRUG PRODUCTS. TRIMETAZIDINE IS AN EFFECTIVE TREATMENT OF PATIENTS WITH ISCHEMIC HEART DISEASE

Рациональная фармакотерапия в кардиологии, 2015
Aim. To study the possibility of enhancing the antianginal effect of long-acting nitrates by their combination with trimetazidine in patients with stable angina. Material and methods.
L. E. Chekuldaeva, S. V. Obuhova, A. A. Simakov, L. V. Poljaeva, E. I. Rjazanova   +4 more
doaj   +3 more sources

Recent Advancement of Medical Patch for Transdermal Drug Delivery

Medicina, 2023
Transdermal patches are a non-invasive method of drug administration. It is an adhesive patch designed to deliver a specific dose of medication through the skin and into the bloodstream throughout the body.
Won Fen Wong, Kuan Ping Ang, Gautam Sethi, Chung Yeng Looi   +3 more
doaj   +1 more source

Nitroglycerin for treatment of retained placenta: A randomised, placebo-controlled, multicentre, double-blind trial in the UK.

PLoS Medicine, 2019
BackgroundRetained placenta following vaginal delivery is a major cause of postpartum haemorrhage. Currently, the only effective treatments for a retained placenta are the surgical procedures of manual removal of placenta (MROP) and uterine curettage ...
Fiona C Denison, Kathryn F Carruthers, Jemma Hudson, Gladys McPherson, Gin Nie Chua, Mathilde Peace, Jane Brewin, Nina Hallowell, Graham Scotland, Julia Lawton, John Norrie, Jane E Norman, GOT-IT investigator team   +12 more
doaj   +1 more source

Primary erythromelalgia mainly manifested by hypertensive crisis: A case report and literature review

Frontiers in Pediatrics, 2022
BackgroundPrimary erythrocytic (PEM) is a rare autosomal dominant single gene disease. Most of the changes of gene loci can be found by whole exon gene sequencing, and the clinical symptoms and patient survival can be improved by specific site-to-site ...
Shuo Feng, Zhanwen He, Liping Que, Xiangyang Luo, Liyang Liang, Dongfang Li, Lijun Qin   +6 more
doaj   +1 more source

Perspectives of nanotechnologies in clinical neurology

Анналы клинической и экспериментальной неврологии, 2017
Nanotechnologies is a new and rapidly developing field of science and engineering related to targeted manipulation of objects sized within the nano-diapason (1091012 m); this means principally new characteristics and qualities of the respective systems ...
R. D. Seifulla, Z. A. Suslina, E. V. Kulykova, E. K. Kim, A. B. Timofeev, S. N. Illarioshkin, E. A. Rozhkova   +6 more
doaj   +1 more source

Registration of Medicines in the Soviet Control and Licensing System on the Example of the Cardiological Drug Trinitrolong

Рациональная фармакотерапия в кардиологии, 2021
The article presents the history of the study and registration in the USSR of the buccal form of nitroglycerin (trinitrolong) in the 1970s and 1980s, based on a number of author's publications, documentary evidence and oral stories of participants in ...
A. N. Petrenko, P. A. Vasiliev, S. Yu. Martsevich, N. P. Kutishenko, O. I. Zvonareva   +4 more
doaj   +1 more source

Efficacy of egg yolk and nitroglycerin ointment as treatments for acute anal fissures: A randomized clinical trial study

Electronic Physician, 2016
Background: Acute anal fissure as a common disease in society has several etiologies and manifestations such as severe anal pain and bleeding. Nitroglycerin ointment 0.2% is the most common topical treatment used.
Masoumeh Salari, Roshanak Salari, Maliheh Dadgarmoghadam, Majid Khadem-Rezaiyan, Mousalreza Hosseini   +4 more
doaj   +1 more source

Delta opioid receptors in Nav1.8 expressing peripheral neurons partially regulate the effect of delta agonist in models of migraine and opioid-induced hyperalgesia

Neurobiology of Pain, 2022
Migraine is one of the most common pain disorders and causes disability in millions of people every year. Delta opioid receptors (DOR) have been identified as a novel therapeutic target for migraine and other headache disorders.
Zachariah Bertels, Isaac J. Dripps, Pal Shah, Laura S. Moye, Alycia F. Tipton, Kendra Siegersma, Amynah A. Pradhan   +6 more
doaj   +1 more source

Immunohistochemical evidences of anticancer actions of metformin with other repurposed drug combinations and correlation with hamster fibrosarcoma tumor size [PDF]

Journal of the Serbian Chemical Society
The aim was to detect and correlate anticancer effects of metformin in combinations with other repurposed drugs, already registered for other indications, which may be immediately applied and clinically investigated in oncology, reducing the time and ...
Popović Jovan K., Popović Dušica J., Popović Kosta J., Miljković Dejan, Lalošević Dušan, Dolićanin Zana, Čapo Ivan   +6 more
doaj   +1 more source

Effects of metformin and its combinations with other repurposed drugs on fibrosarcoma in hamsters [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. Many drugs registered for various other indications can act selectively on tumor receptors, signaling pathways, metabolic processes, bioenergetic factors, enzymes, proteins and genes that regulate tumor proliferation, apoptosis ...
Popović Dušica J., Popović Kosta J., Lalošević Dušan, Popović Jovan K.   +3 more
doaj   +1 more source