Results 31 to 40 of about 3,692,508 (293)
Monitoring of Cardiorespiratory Parameters in Rats—Validation Based on Pharmacological Stimulation
The methods used in preclinical studies should minimize the suffering and the number of animals but still provide precise and consistent results enabling the introduction of drug candidates into the phase of clinical trials.
Joanna Miklosz+4 more
doaj +1 more source
Objective To investigate the potential intraocular pressure (IOP)‐lowering effects of nitric oxide (NO)‐donating compounds in healthy canine eyes Methods A total of 79 dogs were divided into 3 groups in a masked, controlled and randomised study. Group N (
Parker A. Wilcox+3 more
doaj +1 more source
AMI with normal ECG and biomarkers of cardiac injury is exceedingly rare. The clinical manifestations of AMI were complex and varied, especially that the patients with atypical AMI were increasing in clinical practice. Caution should be exercised to exclude AMI in patients with chest pain and both normal ECG and biomarkers of cardiac injury.
Ke‐Lan Zha, Wen Chen, Qiang Ye
wiley +1 more source
Flap necrosis is a common complication after mastectomy, and nitroglycerin (NTG) ointment has been used successfully to treat it. However, it is not clear whether topical NTG can completely prevent the occurrence of flap necrosis after breast cancer ...
Pu Wang+4 more
semanticscholar +1 more source
Aim. To study the possibility of enhancing the antianginal effect of long-acting nitrates by their combination with trimetazidine in patients with stable angina. Material and methods.
L. E. Chekuldaeva+4 more
doaj +3 more sources
Nanoliposomal Nitroglycerin Exerts Potent Anti-Inflammatory Effects. [PDF]
Nitroglycerin (NTG) markedly enhances nitric oxide (NO) bioavailability. However, its ability to mimic the anti-inflammatory properties of NO remains unknown. Here, we examined whether NTG can suppress endothelial cell (EC) activation during inflammation
Ardekani, Soroush+8 more
core +1 more source
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra+3 more
wiley +1 more source
Use of Meldonium in the Treatment of Patients with Coronary Artery Disease and Concomitant Arterial Hypertension [PDF]
Coronary artery disease (CAD) remains one of the leading causes of mortality and disability in Ukraine. Arterial hypertension (AH) is one of the most common diseases and a leading risk factor for coronary artery disease.The aim of the work is to evaluate
Vakaliuk, I. (Ihor)+1 more
core +3 more sources
BackgroundPrimary erythrocytic (PEM) is a rare autosomal dominant single gene disease. Most of the changes of gene loci can be found by whole exon gene sequencing, and the clinical symptoms and patient survival can be improved by specific site-to-site ...
Shuo Feng+6 more
doaj +1 more source
Perspectives of nanotechnologies in clinical neurology
Nanotechnologies is a new and rapidly developing field of science and engineering related to targeted manipulation of objects sized within the nano-diapason (1091012 m); this means principally new characteristics and qualities of the respective systems ...
R. D. Seifulla+6 more
doaj +1 more source