Results 31 to 40 of about 11,777 (217)

P153 Radial-finger Pulse Wave Velocity as a Measure of Microvascular Stiffness: Feasibility and Response to Nitroglycerin

Artery Research, 2020
Background/Objectives: We previously demonstrated a different regional stiffness response of elastic and muscular arteries after the administration of nitroglycerin, leading to an alteration of aortic-brachial stiffness gradient.
Catherine Fortier, Mohsen Agharazii, Charles-Antoine Garneau, Karine Marquis   +3 more
doaj   +2 more sources

THE CHOICE OF NITRATE THERAPY IN PATIENTS WITH STABLE ANGINA: COMPARATIVE STUDY OF ISOSORBIDE DINITRATE (IN USUAL TABLETS) WITH ISOSORBIDE-5-MONONITRATE (IN VARIOUS PRESENTATIONS)

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study efficacy and tolerability of isosorbide-5-mononitrate (IMN) in various presentations in comparison with isosorbide dinitrate (IDN) in usual tablets in patients with stable angina.Material and Methods.
V. A. Egoro, E. V. Shilova, S. Y. Martsevich   +2 more
doaj   +1 more source

Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation

Biomolecules, 2022
Glutathione-S-transferases (GSTs) are highly promiscuous in terms of their interactions with multiple proteins, leading to various functions. In addition to their classical detoxification roles with multi-drug resistance-related protein-1 (MRP1), more ...
Tiffany M. Russell, Des R. Richardson
doaj   +1 more source

Effect of N-methyl-d-aspartate (NMDA) receptor antagonist combination as adjuvant to general anesthesia in functional endoscopic sinus surgery

Ain Shams Journal of Anesthesiology, 2019
Background This randomized, placebo-controlled, double-blind study was designed to assess controlled hypotension using N-methyl-d-aspartate (NMDA) receptor antagonists in patients undergoing functional endoscopic sinus surgery under general anesthesia ...
Karim Youssef Kamal Hakim, Wahba Zakaria Wahba   +1 more
doaj   +1 more source

Search for Therapeutic Agents for Cardiac Arrest Using a Drug Discovery Tool and Large-Scale Medical Information Database

Frontiers in Pharmacology, 2019
The survival rate of cardiac arrest patients is less than 10%; therefore, development of a therapeutic strategy that improves their prognosis is necessary. Herein, we searched data collected from medical facilities throughout Japan for drugs that improve
Yoshito Zamami, Yoshito Zamami, Takahiro Niimura, Toshihiro Koyama, Yuta Shigemi, Yuki Izawa-Ishizawa, Mizuki Morita, Ayako Ohshima, Keisaku Harada, Toru Imai, Hiromi Hagiwara, Naoto Okada, Mitsuhiro Goda, Kenshi Takechi, Masayuki Chuma, Yutaka Kondo, Koichiro Tsuchiya, Shiro Hinotsu, Mitsunobu R. Kano, Keisuke Ishizawa, Keisuke Ishizawa   +20 more
doaj   +1 more source

Characterization of the peripheral FAAH inhibitor, URB937, in animal models of acute and chronic migraine

Neurobiology of Disease, 2021
Inhibiting the activity of fatty-acid amide hydrolase (FAAH), the enzyme that deactivates the endocannabinoid anandamide, enhances anandamide-mediated signaling and holds promise as a molecular target for the treatment of human pathologies such as ...
Rosaria Greco, Chiara Demartini, Annamaria Zanaboni, Ilenia Casini, Roberto De Icco, Angelo Reggiani, Alessandra Misto, Daniele Piomelli, Cristina Tassorelli   +8 more
doaj   +1 more source

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet, Siddhartha Mengi, David Garcia Labbé, Can Manh Nguyen, Jean‐Michel Paradis   +4 more
wiley   +1 more source

Liquorice ingestion attenuates vasodilatation via exogenous nitric oxide donor but not via β2-adrenoceptor stimulation.

PLoS ONE, 2019
We examined the effect of liquorice ingestion on haemodynamic responses to exogenous nitric oxide donor (nitroglycerin) and β2-adrenoceptor agonist (salbutamol), and 11β-hydroxysteroid dehydrogenase activity, in 21 volunteers and 21 reference subjects ...
Elina J Hautaniemi, Antti J Tikkakoski, Arttu Eräranta, Mika Kähönen, Esa Hämäläinen, Ursula Turpeinen, Heini Huhtala, Jukka Mustonen, Ilkka H Pörsti   +8 more
doaj   +1 more source

Coronary Slow Flow and No‐Reflow During Percutaneous Coronary Intervention: Contemporary Insights Into Imaging‐Guided Prediction, Prevention, and Management

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Coronary slow flow (SF) and no‐reflow (NR) are clinically significant complications of percutaneous coronary intervention (PCI), particularly in ST‐segment elevation myocardial infarction (STEMI) and saphenous vein graft (SVG) interventions. Angiographically defined as impaired myocardial perfusion despite restored epicardial patency, SF/NR ...
Bharat Khialani, Eran Sim, George Touma, Sarah Fairley, Cuneyt Ada, Bernard Wong   +5 more
wiley   +1 more source

The plasma fibrinogen levels in the nitroglycerin-induced chronic migraine rat model and its association between migraine-associated vestibular dysfunction

Frontiers in Neurology, 2023
The purpose of this study was to measure the vestibular function and plasma fibrinogen level in the nitroglycerin (NTG)-induced chronic migraine rats, and explore the effect of defibrinogenation on migraine and associated vestibular dysfunction.
Jilei Zhang, Yixin Zhao, Yuanyuan Jing, Lin Han, Xin Ma, Lisheng Yu, Tongxiang Diao   +6 more
doaj   +1 more source