Results 41 to 50 of about 11,777 (217)

Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav, Benny Neumark, Oneg Elkabets, Alex Yakovchuk   +3 more
wiley   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

NEW POSSIBILITIES OF TREATMENT OF PATIENTS WITH ISHEMIC HEART DISEASE AND STABLE ANGINA

Медицинский совет, 2016
Purpose. To e valuate clinical effectiveness of a new dosage form of trimetazidine for a single administration per day (Deprenorm MV 70) in patients with ischemic heart disease (IHD) and stable angina.Materials and methods. The study included 85 patients
A. A. SIMAKOV, M. I. PANINA
doaj   +1 more source

Measurement and management of adult blood pressure in the peri‐operative period: updated guidelines from the Association of Anaesthetists and the British and Irish Hypertension Society

Anaesthesia, EarlyView.
Summary Introduction Maintaining stable blood pressure during surgery is a key responsibility of anaesthetists. Peri‐operative omission and reintroduction of antihypertensive drugs, general anaesthesia, neuraxial and regional techniques can all cause significant fluctuations in blood pressure, particularly in patients with hypertension. Since the first
Terry McCormack, Alex Wickham, Sinéad T. J. McDonagh, Matthew D. Wiles, Luca Faconti, Rachael Brooks, Simon G. Anderson, Andrew Hartle   +7 more
wiley   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

The Positive Report Of benson Relaxation For Acute Miocard Infark Pain: A Case Report Study

South East Asia Nursing Research, 2021
Structured Acute Myocardial Infarction (AMI) is myocardial necrosis caused by inadequate blood supply due to acute blockage of the coronary arteries.
Dwi Nur Rahmantika Puji Safitri, Sri Rejeki, Edy Soesanto, Muhammad Ali   +3 more
doaj   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Efficacy and disposal of drugs after the expiry date

The Egyptian Journal of Internal Medicine, 2019
Every drug manufacturer is legally bound to display the date of expiry on all pharmaceutical products. Excluding certain medicines such as nitroglycerin, insulin, epinephrine, and tetracycline, most medicines stored under reasonable conditions retain at ...
Gurmeet S Sarla
doaj   +1 more source

Evaluating associations of migraine‐related vertigo

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective We set out to examine detailed phenotypic data from our clinic for associations of vertigo in chronic migraine. Background Vertigo is a non‐canonical, common symptom of migraine. Little is known about its associations with other symptoms within the migraine phenotype.
Nazia Karsan, Nicolas Vandenbussche, Robyn Jenia‐Wilcha, Pubudu Amarasena, Pannathat Soontrapa, Karthik Nagaraj, Carlo Lastarria Perez, Peter J. Goadsby   +7 more
wiley   +1 more source

Persistent postural‐perceptual dizziness versus vestibular migraine: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This article reviews the differences and similarities between persistent postural‐perceptual dizziness (PPPD) and vestibular migraine. Background PPPD is considered a chronic functional vestibular disorder characterized by persistent dizziness, unsteadiness, nonspinning vertigo, and often exacerbated by upright posture, movement, or ...
David Moreno‐Ajona
wiley   +1 more source