Results 41 to 50 of about 3,729,717 (272)

Registration of Medicines in the Soviet Control and Licensing System on the Example of the Cardiological Drug Trinitrolong

Рациональная фармакотерапия в кардиологии, 2021
The article presents the history of the study and registration in the USSR of the buccal form of nitroglycerin (trinitrolong) in the 1970s and 1980s, based on a number of author's publications, documentary evidence and oral stories of participants in ...
A. N. Petrenko, P. A. Vasiliev, S. Yu. Martsevich, N. P. Kutishenko, O. I. Zvonareva   +4 more
doaj   +1 more source

Triptans and CGRP blockade - impact on the cranial vasculature [PDF]

, 2017
The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide ...
Alejandro Labastida-Ramírez, Anne Luise Vollesen, Christian Lampl, Francesca Cortese, Francesca Marchese, Lanfranco Pellesi, Messoud Ashina, Michele Romoli, On behalf of the School of Advanced Studies of the European Headache Federation (EHF-SAS), Silvia Benemei   +9 more
core   +3 more sources

Isosorbide dinitrate, with or without hydralazine, does not reduce wave reflections, left ventricular hypertrophy, or myocardial fibrosis in patients with heart failure with preserved ejection fraction [PDF]

, 2017
Background-Wave reflections, which are increased in patients with heart failure with preserved ejection fraction, impair diastolic function and promote pathologic myocardial remodeling.
Akers, Scott, Beraun, Melissa, Chirinos, Julio A., Chittams, Jesse, Haines, Philip G., Koppula, Maheswara R., Rawat, Deepa, Segers, Patrick, Shiva-Kumar, Prithvi, Soto-Calderon, Haideliza, Townsend, Raymond R., Varakantam, Swapna, Witschey, Walter R., Zamani, Payman   +13 more
core   +1 more source

Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans [PDF]

, 2015
Hypoxic conditions favour the reduction of nitrite to nitric oxide (NO) to elicit vasodilatation, but the mechanism(s) responsible for bioconversion remains ill defined.
Alexander, Alexander, Angelo, Badejo, Bailey, Baliga, Basu, Chen, Cosby, D'Souza, Dejam, DiFabio, Doyle, Furchgott, Ghosh, Gladwin, Golwala, Greenstein, Huellner, Huffman, Irvine, Johansson, Keith, Kollau, Koppaka, Larsen, Li, Lundberg, Mackenzie, Madhani, Maher, Maher, Marti, Ormerod, Paneni, Pawson, Perlman, Pinder, Tiso, Totzeck   +39 more
core   +2 more sources

Recurrent vasovagal syncope: comparison between clomipramine and nitroglycerin as drug challenges during head-up tilt testing.

European Heart Journal, 2009
AIMS To compare the responses between clomipramine, a centrally acting substance, and nitroglycerin, with mainly peripheral action, when each drug is used during tilt test for the induction of vasovagal syncope (VVS).
P. Flevari, D. Leftheriotis, Christophoros Komborozos, K. Fountoulaki, N. Dagres, G. Theodorakis, D. Kremastinos   +6 more
semanticscholar   +1 more source

Immunohistochemical evidences of anticancer actions of metformin with other repurposed drug combinations and correlation with hamster fibrosarcoma tumor size [PDF]

Journal of the Serbian Chemical Society
The aim was to detect and correlate anticancer effects of metformin in combinations with other repurposed drugs, already registered for other indications, which may be immediately applied and clinically investigated in oncology, reducing the time and ...
Popović Jovan K., Popović Dušica J., Popović Kosta J., Miljković Dejan, Lalošević Dušan, Dolićanin Zana, Čapo Ivan   +6 more
doaj   +1 more source

Pharmacy intervention at an intensive care rehabilitation clinic [PDF]

, 2016
Introduction: During an intensive care stay, patients often have their chronic medications withheld for a variety of reasons and new drugs commenced [1].
Daniel, M., Devine, H., Fenlon, C., Kinsella, J., MacTavish, P., McPeake, J., Quasim, T.   +6 more
core   +1 more source

Nesiritide: Harmful or Harmless? [PDF]

, 2006
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90328/1/phco.26.10.1465 ...
Fett DL, Francis GS, Heywood JT, Heywood JT, Ikram H, Jensen KT, Jo Ellen Rodgers, Lainchbury JG, Marcus LS, Michael P Dorsch, Peacock WF, Van der Zander K, Yoshirmura M   +12 more
core   +1 more source

Effects of metformin and its combinations with other repurposed drugs on fibrosarcoma in hamsters [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. Many drugs registered for various other indications can act selectively on tumor receptors, signaling pathways, metabolic processes, bioenergetic factors, enzymes, proteins and genes that regulate tumor proliferation, apoptosis ...
Popović Dušica J., Popović Kosta J., Lalošević Dušan, Popović Jovan K.   +3 more
doaj   +1 more source

Bench-to-bedside review : targeting antioxidants to mitochondria in sepsis [PDF]

, 2010
Peer reviewedPublisher ...
A Dhanasekaran, A Dyson, A Filipovska, AL Hill, AM James, B Bedogni, BE Minter, CA Macias, CC Chuang, CE Cross, D Brealey, D Brealey, D Brealey, D Graham, DA Lowes, DA Lowes, DP Jones, E Borrelli, ED Crouser, ED Crouser, F Arnalich, FN Gellerich, G Escames, G Escames, GF Kelso, GS Supinski, H Bayir, H Bohrer, H Zhang, HC Cowley, Helen F Galley, HF Galley, HF Galley, HF Galley, HF Goode, I Spasojević, I Vanhorebeek, J Ripcke, JC Marshall, JF Turrens, JJ Pandit, JV Esplugues, K Yassen, K Zhao, KS Roser, L Packer, M Qunitero, MD Wheeler, MD Wheeler, MP Fink, MP Fink, MP Murphy, MW Fariss, P Ghafourifar, P Wipf, RAJ Smith, RAJ Smith, RL Paterson, RO Poyton, S González-Rubio, S Rinaldi, SS Sheu, V Mishra, V Vanasco, VJ Adlam, VP Skulachev, W Droge, Z Lacza   +67 more
core   +2 more sources