Results 51 to 60 of about 3,729,717 (272)

P153 Radial-finger Pulse Wave Velocity as a Measure of Microvascular Stiffness: Feasibility and Response to Nitroglycerin

open access: yesArtery Research, 2020
Background/Objectives: We previously demonstrated a different regional stiffness response of elastic and muscular arteries after the administration of nitroglycerin, leading to an alteration of aortic-brachial stiffness gradient.
Catherine Fortier   +3 more
doaj   +2 more sources

THE CHOICE OF NITRATE THERAPY IN PATIENTS WITH STABLE ANGINA: COMPARATIVE STUDY OF ISOSORBIDE DINITRATE (IN USUAL TABLETS) WITH ISOSORBIDE-5-MONONITRATE (IN VARIOUS PRESENTATIONS)

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study efficacy and tolerability of isosorbide-5-mononitrate (IMN) in various presentations in comparison with isosorbide dinitrate (IDN) in usual tablets in patients with stable angina.Material and Methods.
V. A. Egoro   +2 more
doaj   +1 more source

Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort. [PDF]

open access: yes, 2016
Nitrates, such as cardiac therapeutics and food additives, are common headache triggers, with nitric oxide playing an important role. Facultative anaerobic bacteria in the oral cavity may contribute migraine-triggering levels of nitric oxide through the ...
Antonio Gonzalez   +6 more
core   +2 more sources

Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation

open access: yesBiomolecules, 2022
Glutathione-S-transferases (GSTs) are highly promiscuous in terms of their interactions with multiple proteins, leading to various functions. In addition to their classical detoxification roles with multi-drug resistance-related protein-1 (MRP1), more ...
Tiffany M. Russell, Des R. Richardson
doaj   +1 more source

Effect of N-methyl-d-aspartate (NMDA) receptor antagonist combination as adjuvant to general anesthesia in functional endoscopic sinus surgery

open access: yesAin Shams Journal of Anesthesiology, 2019
Background This randomized, placebo-controlled, double-blind study was designed to assess controlled hypotension using N-methyl-d-aspartate (NMDA) receptor antagonists in patients undergoing functional endoscopic sinus surgery under general anesthesia ...
Karim Youssef Kamal Hakim   +1 more
doaj   +1 more source

Search for Therapeutic Agents for Cardiac Arrest Using a Drug Discovery Tool and Large-Scale Medical Information Database

open access: yesFrontiers in Pharmacology, 2019
The survival rate of cardiac arrest patients is less than 10%; therefore, development of a therapeutic strategy that improves their prognosis is necessary. Herein, we searched data collected from medical facilities throughout Japan for drugs that improve
Yoshito Zamami   +20 more
doaj   +1 more source

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]

open access: yes, 2019
The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole   +5 more
core   +1 more source

Liquorice ingestion attenuates vasodilatation via exogenous nitric oxide donor but not via β2-adrenoceptor stimulation.

open access: yesPLoS ONE, 2019
We examined the effect of liquorice ingestion on haemodynamic responses to exogenous nitric oxide donor (nitroglycerin) and β2-adrenoceptor agonist (salbutamol), and 11β-hydroxysteroid dehydrogenase activity, in 21 volunteers and 21 reference subjects ...
Elina J Hautaniemi   +8 more
doaj   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Topical Nitroglycerin for Osteoporosis: Old Drug New Application

open access: yesJournal of South Asian Federation of Obstetrics and Gynaecology, 2016
ABSTRACTOsteoporosis is a progressive bone disease characterized by a decrease in the bone mass and density, which can lead to an increased risk of fracture. Multiple treatments have been formulated for it like calcium, vitamin D supplements, bisphosphonates, raloxifene, hormone replacement therapies, teriparatide and calcitonin.
Omkar Singh   +2 more
openaire   +2 more sources

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