Results 71 to 80 of about 3,766,051 (278)

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

The Positive Report Of benson Relaxation For Acute Miocard Infark Pain: A Case Report Study

South East Asia Nursing Research, 2021
Structured Acute Myocardial Infarction (AMI) is myocardial necrosis caused by inadequate blood supply due to acute blockage of the coronary arteries.
Dwi Nur Rahmantika Puji Safitri, Sri Rejeki, Edy Soesanto, Muhammad Ali   +3 more
doaj   +1 more source

Nitroglycerin reverts clinical manifestations of poor peripheral perfusion in patients with circulatory shock [PDF]

, 2014
Introduction: Recent clinical studies have shown a relationship between abnormalities in peripheral perfusion and unfavorable outcome in patients with circulatory shock.
Bakker, J. (Jan), Bommel, J. (Jasper) van, Genderen, M.E. (Michel) van, Jansem, T. (Tim), Klijn, E. (Elko), Lima, A.A.P. (Alexandre )   +5 more
core   +4 more sources

Blood Pressure Effects and Risk of Hypotension due to Intravenous Furosemide in Acute Decompensated Heart Failure

Academic Emergency Medicine, EarlyView.
ABSTRACT Objective We quantified the magnitude of systolic blood pressure (SBP) adverse effects associated with intravenous furosemide (IVFu), compared to other factors, during treatment for acute decompensated heart failure (ADHF). Methods Continuous BP monitoring (598.2 person‐hours, 91,210 observations) before and after IVFu was performed in a ...
Nicholas E. Harrison, Meghana Bhaskara, Kyle Wilson, Ankit A. Desai, Nicholas Montelauro, Phillip Levy, Peter Pang, Robert R. Ehrman   +7 more
wiley   +1 more source

Intravenous methadone for pain management in cardiac surgery: a randomised controlled trial with plasma concentration analysis*

Anaesthesia, EarlyView.
Summary Introduction Postoperative pain after cardiac surgery remains significant despite the administration of opioids. Methadone may improve pain control and decrease the need for postoperative opioids. Randomised controlled trials, however, are limited and the effects of cardiopulmonary bypass on methadone pharmacokinetics are unclear.
Henry Man Kin Wong, Veronica Ka Wai Lai, Sandra Lok Ching Chiu, Wai Tat Wong, Siu Kwan Wo, Joan Zhong Zuo, Xiaodong Liu, Randolph Hung Leung Wong, Kwok Ming Ho   +8 more
wiley   +1 more source

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]

, 2019
The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole, Differ, Christopher, Klatte-Schulz, Franka, Knaus, Petra, Minkwitz, Susann, Wildemann, Britt   +5 more
core   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Efficacy and disposal of drugs after the expiry date

The Egyptian Journal of Internal Medicine, 2019
Every drug manufacturer is legally bound to display the date of expiry on all pharmaceutical products. Excluding certain medicines such as nitroglycerin, insulin, epinephrine, and tetracycline, most medicines stored under reasonable conditions retain at ...
Gurmeet S Sarla
doaj   +1 more source

A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve. [PDF]

, 2015
AimsThe mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear.
Anderson, R David, Bairey Merz, C Noel, Berman, Daniel S, Brown, Garrett H, Cook-Wiens, Galen, Handberg, Eileen M, Mehta, Puja K, Minissian, Margo B, Pepine, Carl J, Petersen, John W, Rogatko, André, Shaw, Leslee J, Shufelt, Chrisandra L, Shuster, Jonathan J, Thomson, Louise EJ, Wei, Janet   +15 more
core   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source