Results 141 to 150 of about 364 (179)

PMR analysis of nitroquinoline 1‐Oxides

Journal of Heterocyclic Chemistry, 1972
AbstractChemical shifts and coupling values obtained from the 100 MHz pmr spectra of 12 nitrosubstituted quinoline 1‐oxide derivatives are presented. Spin‐spin decoupling, application of the paramagnetic shift reagent tris‐(1,1,1,2,2,3,3‐heptafluoro‐7,7‐dimethyl‐4,6‐octanedione) europium (III), and calculations of theoretical spectra were used in ...
Robert Roe, J. S. Paul, P.O'B. Montgomery   +2 more
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ChemInform Abstract: Oxidative Methylamination of Nitroquinolines.

ChemInform, 1993
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. WOZNIAK, M. GRZEGOZEK
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Interactions of 4-nitroquinoline 1-oxide with deoxyribodinucleotides

Biochemistry, 1979
The interactions of 4-nitroquinoline 1-oxide (NQO), a potent mutagen and carcinogen, with several self- and non-self-complementary deoxydinucleotides were probed by using absorption spectra of the charge transfer bands and 1H and 13C NMR spectra. Absorption spectra were analyzed by using Benesi-Hildebrand-type equations to yield stoichiometries and ...
S A, Winkle, I, Tinoco
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Reduction of 6‐nitroquinoline with phosphine

Recueil des Travaux Chimiques des Pays-Bas, 1964
AbstractReduction of 6‐nitroquinoline with phosphine under the conditions described by Buckler yields 6,6′‐azo‐5,5′‐diquinolyl along with 6,6′‐azoxyquinoline.
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Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series

Bioorganic & Medicinal Chemistry, 2015
An antileishmanial pharmacomodulation at position 4 of 8-nitroquinolin-2(1H)-one was conducted by using the Sonogashira and Suzuki-Miyaura coupling reactions. A series of 25 derivatives was tested in vitro on the promastigote stage of Leishmania donovani along with an in vitro cytotoxicity evaluation on the human HepG2 cell line.
Kieffer, Charline, Cohen, Anita, Verhaeghe, Pierre, Paloque, Lucie, Hutter, Sébastien, Castera-Ducros, Caroline, Laget, Michèle, Rault, Sylvain, Valentin, Alexis, Rathelot, Pascal, Azas, Nadine, Vanelle, Patrice   +11 more
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Mutagenicity of 4-nitroquinoline 1-oxide in the Muta™Mouse

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 1999
As part of a collaborative study, the Mammalian Mutagenesis Study Group (MMS), a sub-organization of the Environmental Mutagen Society of Japan (JEMS) conducted mutagenicity tests in MutaMouse. Using a positive selection method, we studied the organ-specificity and time dependence of mutation induction by 4-nitroquinoline 1-oxide (4NQO).
M, Nakajima, M, Kikuchi, K, Saeki, Y, Miyata, M, Terada, F, Kishida, R, Yamamoto, C, Furihata, S W, Dean   +8 more
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Vicarious Nucleophilic Substitution in Nitroquinolines¹⁾

Liebigs Annalen der Chemie, 1986
Abstract5‐Nitro‐, 6‐nitro‐, and 8‐nitroquinoline react with the carbanions of chloromethyl phenyl sulfone, chloro‐N,N‐dimethylmethanesulfonamide and substituted acetonitriles XCH2CN (X = OPh, SPh, Cl) giving products of the vicarious nucleophilic substitution of hydrogen predominantly or exclusively at positions 6, 5, and 7, respectively.
Mieczyslaw Mąkosza, Andrzej Kinowski, Witold Danikiewicz, Boguslaw Mudryk   +3 more
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Molecular Biology of the Carcinogen, 4-Nitroquinoline 1-Oxide

1976
Publisher Summary Studies on chemical carcinogenesis have three main purposes. First is to elucidate carcinogenic mechanisms, second is to prevent possible carcinogenic hazard due to chemicals in the environment, and third is to provide clinical model systems in experimental animals. Recent studies on chemical carcinogens and mutagens have shown that,
M, Nagao, T, Sugimura
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Caffeine inhibits cell transformation by 4-nitroquinoline-1-oxide

Nature, 1975
SOMATIC mutation has been considered a likely initiating step in chemical carcinogenesis1–3, chiefly because of the close correlation between the mutagenic and carcinogenic activity of various chemicals4–6. Study of cells from patients with disease predisposing to a high incidence of cancer, such as xeroderma pigmentosum and Fanconi's anaemia, has ...
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ChemInform Abstract: AMINOMETHYLATION OF 6‐HYDROXY‐8‐NITROQUINOLINE

Chemischer Informationsdienst, 1984
AbstractAus dem Hydroxy‐nitro‐chinolin (I) erhält man nach Mannich mit sekundären Aminen (II) und Formaldehyd (III) die Aminomethylderivate (IV).
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