Results 131 to 140 of about 936,507 (305)

Sheet‐Size‐Dependent Mosaicity of 2D Phyllosilicate Membranes

open access: yesAdvanced Science, EarlyView.
This study explores how the size of 2D vermiculite sheets affects the structure of laminar membranes. High‐resolution x‐ray diffraction reveals how sheet size governs structural disorder and crystallinity. These changes directly impact ion permeability.
Min A Kim   +6 more
wiley   +1 more source

N-Tox® - Early warning of nitrification toxicity for activated sludge treatment [PDF]

open access: yes, 2006
N-Tox® is a new technique for evaluating the nitrification efficiency in industrial or municipal activated sludge systems, using direct measurement of nitrous oxide (N20) as an indicator of nitrification failure.
Stephenson, Tom   +3 more
core   +1 more source

Right iliac deep vein thrombosis and pulmonary embolism associated with recreational nitrous oxide: a case report

open access: yesInternational Journal of Emergency Medicine
Background The recreational use of nitrous oxide is becoming increasingly common among teenagers and young adults. Since 2018, the use of nitrous oxide has increased exponentially and has become a public health problem.
Thomas Bizouard   +4 more
doaj   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang   +7 more
wiley   +1 more source

Subacute combined degeneration from nitrous oxide abuse

open access: yesRadiology Case Reports
Nitrous oxide is an anesthetic medication which can also be recreationally abused in the form of whippet canisters. Its prolonged abuse can interfere with Vitamin B12 metabolism and lead to its functional deficiency.
Harjinder Singh, MD   +3 more
doaj   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Is nitrous oxide next? [PDF]

open access: yesAnaesthesia, 1989
M B, Smith, N W, Penfold
openaire   +2 more sources

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

open access: yesAdvanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou   +18 more
wiley   +1 more source

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

open access: yesAdvanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu   +8 more
wiley   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia   +10 more
wiley   +1 more source

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