Cerebral Venous Sinus Thrombosis Following Nitrous Oxide Abuse: A Clinical Reminder of a Growing Trend. [PDF]
Kober M +4 more
europepmc +1 more source
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
Recreational nitrous oxide abuse and myeloneuropathy among Vietnamese youth: A descriptive study of 35 cases. [PDF]
Dang DN, Hong ALN, Dang BN.
europepmc +1 more source
Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang +22 more
wiley +1 more source
Mechanistic understanding of nitrate reduction as the dominant production pathway of nitrous oxide in marine oxygen minimum zones. [PDF]
Sun X +9 more
europepmc +1 more source
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li +14 more
wiley +1 more source
Liming-Induced Nitrous Oxide Emissions from Acidic Soils Dominated by Stimulative Nitrification. [PDF]
Xiang X +6 more
europepmc +1 more source
Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang +16 more
wiley +1 more source
From "Laughing Gas" to "Galaxy Gas": An Updated Review on the Neurological, Pathologic, and Psychiatric Sequelae of Nitrous Oxide Abuse. [PDF]
Lal Vallath A +4 more
europepmc +1 more source

