Results 251 to 260 of about 3,169,653 (393)

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Electron shuttling promotes denitrification and mitigates nitrous oxide emissions in lakes. [PDF]

Nat Commun
Song K, Xiao Y, Wang Y, Deng M, Zhou S, Huang Y, Yeerken S, Li L, Wu F.   +8 more
europepmc   +1 more source

Severe Nausea and Vomiting in the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II Trial

Anesthesiology, 2016
P. Myles, M. Chan, J. Kasza, M. Paech, K. Leslie, P. Peyton, D. Sessler, G. Haller, W. Beattie, C. Osborne, J. Sneyd, A. Forbes   +11 more
semanticscholar   +1 more source

High-Resolution Infrared Spectroscopy of van der Waals Clusters of Nitrous Oxide, Carbon Dioxide and OCS-R Complexes

, 2013
J. Norooz Oliaee
openalex   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Nitrous Oxide Production and Hydroxylamine Accumulation in a Partial Nitritation Sequencing Batch Reactor: Comparison of Different Operational Strategies. [PDF]

ACS ES T Water
Olmo L, Carrera J, Pérez J.
europepmc   +1 more source

Global metaanalysis of the nonlinear response of soil nitrous oxide (N2O) emissions to fertilizer nitrogen

Proceedings of the National Academy of Sciences of the United States of America, 2014
I. Shcherbak, N. Millar, G. Robertson
semanticscholar   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Co-creating harm reduction resources with young people who use nitrous oxide: What catches their attention? [PDF]

Harm Reduct J
Kor K, Allan J, Cameron J, Simpson H.
europepmc   +1 more source

Chronic postsurgical pain in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II trial.

British Journal of Anaesthesia, 2016
M. Chan, P. Peyton, P. Myles, K. Leslie, N. Buckley, J. Kasza, M. Paech, W. Beattie, D. Sessler, A. Forbes, S. Wallace, Y. Chen, Y. Tian, W. Wu   +13 more
semanticscholar   +1 more source