Results 271 to 280 of about 3,169,653 (393)

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu   +16 more
wiley   +1 more source

Catatonia induced by nitrous oxide anesthesia in a healthy adolescent: A case report. [PDF]

open access: yesPCN Rep
Kobayashi KS   +5 more
europepmc   +1 more source

Tension Pneumocephalus after Head Injury Associated with Nitrous Oxide Anesthesia for Extracranial Operation

open access: bronze, 1984
Daikai Sadamitsu   +5 more
openalex   +2 more sources

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

open access: yesAdvanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu   +8 more
wiley   +1 more source

Substrate Effect on the Contribution of Ammonium and Urea to Marine Nitrification and Nitrous Oxide Production. [PDF]

open access: yesEnviron Microbiol
Tang W   +10 more
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

open access: yesAdvanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong   +13 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Biochar's role in mitigating soil nitrous oxide emissions: a review and meta-analysis

open access: yes, 2014
M. Cayuela   +5 more
semanticscholar   +1 more source

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