Results 1 to 10 of about 7,196 (266)

Development of Triamcinolone Acetonide-Loaded Nanostructured Lipid Carriers (NLCs) for Buccal Drug Delivery Using the Box-Behnken Design

Molecules, 2018
The aim of this present work was to prepare triamcinolone acetonide (TA)-loaded nanostructured lipid carriers (TA-loaded NLCs) for buccal drug delivery systems using the Box-Behnken design.
Pakorn Kraisit, Narong Sarisuta
exaly   +4 more sources

Cannabidiol-Loaded Nanostructured Lipid Carriers (NLCs) for Dermal Delivery: Enhancement of Photostability, Cell Viability, and Anti-Inflammatory Activity

Pharmaceutics, 2023
The aim of this study was to encapsulate cannabidiol (CBD) extract in nanostructured lipid carriers (NLCs) to improve the chemical stability and anti-inflammatory activity of CBD for dermal delivery.
Boontida Morakul, Varaporn Buraphacheep Junyaprasert, Krisada Sakchaisri, Veerawat Teeranachaideekul   +3 more
doaj   +2 more sources

Insights into nanostructured lipid carriers for the effective delivery of bioactives in swine and poultry health: review [PDF]

Animal Bioscience
Nanostructured lipid carriers (NLCs) are promising in target and efficient delivery of bioactive compounds with high loading capacity of bioactives, better physical stability, better encapsulation efficiency, solubility and bioavailability in comparison ...
Noor Saba, Mohammad Moniruzzaman, Do Thi Cat Toung, Sungyeon Chin, Lin Lat La Min, Adhimoolam Karthikeyan, Dong I. Lee, Ji-Yeon Chun, Taesun Min   +8 more
doaj   +2 more sources

Potential use of Nanostructured Lipid Carriers mediated neuronal delivery of Carbamazepine [PDF]

Nanomedicine Research Journal, 2022
Carbamazepine (CZB) as a medication for epilepsy and anxiety therapy, presenting a complex pharmacokinetic profile and severe side effects. Therefore, the development of strategies that significantly decrease the side effects and frequency of ...
Salar Masoomzadeh, Somayeh Sadighian, Tooba Gholikhani, Kobra Rostamizadeh   +3 more
doaj   +1 more source

Influence of Surface-Modification via PEGylation or Chitosanization of Lipidic Nanocarriers on In Vivo Pharmacokinetic/Pharmacodynamic Profiles of Apixaban

Pharmaceutics, 2023
Nanostructured lipid carriers (NLCs) have been proven to significantly improve the bioavailability and efficacy of many drugs; however, they still have many limitations.
Mohamed F. Zaky, Taha M. Hammady, Shadeed Gad, Abdullah Alattar, Reem Alshaman, Ann Hegazy, Sawsan A. Zaitone, Mamdouh Mostafa Ghorab, Mohamed A. Megahed   +8 more
doaj   +1 more source

Preformulation screening of lipids using solubility parameter concept in conjunction with experimental research to develop ceftriaxone loaded nanostructured lipid carriers [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2023
Development of ceftriaxone loaded nanostructured lipid carriers to increase permeability of ceftriaxone across uninflamed meninges after parenteral administration.
Swarupanjali Padhi, Rupa Mazumder, Shradha Bisht   +2 more
doaj   +1 more source

Targeted Delivery of Pennyroyal via Methotrexate Functionalized PEGylated Nanostructured Lipid Carriers into Breast Cancer Cells; A Multiple Pathways Apoptosis Activator [PDF]

Advanced Pharmaceutical Bulletin, 2023
Purpose: Pennyroyal is a species of the Lamiaceae family with potent anti-cancer and antioxidant properties. Combining this antioxidant with chemotherapeutic agents enhances the effectiveness of these agents by inducing more apoptosis in cancerous cells.
Amin Mahoutforoush, Leila Asadollahi, Hamed Hamishehkar, Soheil Abbaspour-Ravasjani, Atefeh Solouk, Masoumeh Haghbin Nazarpak   +5 more
doaj   +1 more source

Nanostructured lipid carriers mediated transdermal delivery of trandolapril as an impeccable therapeutic approach against hypertension: Development, characterization and in vivo evaluation

OpenNano, 2023
The study aimed to design trandolapril-embedded nanostructured lipid carriers (NLCs) transdermal patch and evaluate its in vitro drug permeation, bioavailability and pharmacokinetics.
Ramankit Jaiswal, Rita Wadetwar
doaj   +1 more source

Repaglinide-loaded nanostructured lipid carriers with different particle sizes for improving oral absorption: preparation, characterization, pharmacokinetics, and in situ intestinal perfusion

Drug Delivery, 2020
Repaglinide-loaded nanostructured lipid carriers (REP-NLCs) with different particle sizes were successfully designed and prepared to investigate the permeation and absorption ability by in situ single-pass intestinal perfusion (SPIP) study and ...
Lei Wu, Lin Zhao, Xitong Su, Peng Zhang, Guixia Ling   +4 more
doaj   +1 more source

Enteric coating of nanostructured lipid carriers (NLCs) and enteric coating of hard gelatin capsules filled with NLCs: Feasibility studies

Pakistan Journal of Pharmaceutical Sciences, 2021
Nanostructured lipid carriers (NLCs) of asenapine maleate (ASPM) were enteric coated with polymethacrylate polymers (Eudragit®) for oral delivery. The present study aimed to compare the feasibility of direct enteric coating of NLCs and enteric coating of
Renuka Suresh Managuli, Meka Sreenivasa Reddy, Kunnatur Balasundara Koteshwara, Srinivas Mutalik   +3 more
doaj   +1 more source