Results 61 to 70 of about 55,457 (295)

How can machine learning predict cholera: insights from experiments and design science for action research

Journal of Water and Health
Cholera is a leading cause of mortality in Nigeria. The two most significant predictors of cholera are a lack of access to clean water and poor sanitary conditions.
Hauwa Ahmad Amshi, Rajesh Prasad, Birendra Kumar Sharma, Saratu Ilu Yusuf, Zaharaddeen Sani   +4 more
doaj   +1 more source

Features of the organization of space-planning solutions for nuclear medicine facilities [PDF]

BIO Web of Conferences
The purpose of this article is to determine the typology of the main functional zones for nuclear medicine facilities (NMF) and the formation of principles that affect the architecture of these typological zones.
Balakina Alevtina, Lempl Jury
doaj   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

The successive projection algorithm as an initialization method for brain tumor segmentation using non-negative matrix factorization. [PDF]

PLoS ONE, 2017
Non-negative matrix factorization (NMF) has become a widely used tool for additive parts-based analysis in a wide range of applications. As NMF is a non-convex problem, the quality of the solution will depend on the initialization of the factor matrices.
Nicolas Sauwen, Marjan Acou, Halandur N Bharath, Diana M Sima, Jelle Veraart, Frederik Maes, Uwe Himmelreich, Eric Achten, Sabine Van Huffel   +8 more
doaj   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Application of spatially related MRF model in NMF hyperspectral unmixing

MATEC Web of Conferences, 2018
Aiming at Non-negative Matrix Factorization (NMF)’s problem of initialization and "local minima" in hyperspectral unmixing, a NMF linear unmixing algorithm with spatial correlation constrains (SCNMF) based on Markov Random Field (MRF) was proposed ...
Yuan Bo
doaj   +1 more source

Detecting heterogeneity in single-cell RNA-Seq data by non-negative matrix factorization [PDF]

PeerJ, 2017
Single-cell RNA-Sequencing (scRNA-Seq) is a fast-evolving technology that enables the understanding of biological processes at an unprecedentedly high resolution.
Xun Zhu, Travers Ching, Xinghua Pan, Sherman M. Weissman, Lana Garmire   +4 more
doaj   +2 more sources

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote homolog detection

BMC Bioinformatics, 2008
Background Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features.
Lee Soo-Young, Lee Jaehyung, Jung Inkyung, Kim Dongsup   +3 more
doaj   +1 more source

Computing a Nonnegative Matrix Factorization -- Provably [PDF]

, 2011
In the Nonnegative Matrix Factorization (NMF) problem we are given an $n \times m$ nonnegative matrix $M$ and an integer $r > 0$. Our goal is to express $M$ as $A W$ where $A$ and $W$ are nonnegative matrices of size $n \times r$ and $r \times m ...
Arora, Sanjeev, Ge, Rong, Kannan, Ravi, Moitra, Ankur   +3 more
core   +1 more source