Results 111 to 120 of about 899,165 (255)

Structural basis of death domain signaling in the p75 neurotrophin receptor

open access: yeseLife, 2015
Death domains (DDs) mediate assembly of oligomeric complexes for activation of downstream signaling pathways through incompletely understood mechanisms.
Zhi Lin   +6 more
doaj   +1 more source

Predicting protein dynamics from structural ensembles

open access: yes, 2015
The biological properties of proteins are uniquely determined by their structure and dynamics. A protein in solution populates a structural ensemble of metastable configurations around the global fold.
Copperman, J., Guenza, M. G.
core   +1 more source

Water‐Compatible SuFEx‐Active Diazonium Linchpin Platform for Rapid Modular Diversification and On‐DNA Functionalization

open access: yesAdvanced Functional Materials, EarlyView.
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong   +5 more
wiley   +1 more source

45: CLOSTRIDIOIDES DIFFICILE IN WESTERN AUSTRALIAN HORSES: A ONE HEALTH FOCUSED GENOMIC ANALYSIS

open access: yesJournal of Global Antimicrobial Resistance, 2022
NMR. Hain-Saunders   +3 more
doaj   +1 more source

Solid State NMR Characterization of Complex Metal Hydrides systems for Hydrogen Storage Applications [PDF]

open access: yes, 2011
Solid state NMR is widely applied in studies of solid state chemistries for hydrogen storage reactions. Use of ^(11)B MAS NMR in studies of metal borohydrides (BH_4) is mainly focused, revisiting the issue of dodecaborane formation and observation of ^(
Bowman, Robert C., Jr.   +4 more
core  

Suppression of Magnetic Order by Pressure in BaFe2As2

open access: yes, 2008
We performed the dc resistivity and the ZF 75As-NMR measurement of BaFe2As2 under high pressure. The T-P phase diagram of BaFe2As2 determined from resistivity anomalies and the ZF 75As-NMR clearly revealed that the SDW anomaly is quite robust against P ...
Fukazawa H.   +11 more
core   +1 more source

Electro‐Steric Ion Confinement in Polyelectrolyte Networks for Robust Nonvolatile Artificial Synapse

open access: yesAdvanced Functional Materials, EarlyView.
Polyelectrolyte stoichiometry governs ion transport and retention in electrolyte‐gated synaptic transistors. A PSS‐rich network creates electro‐steric ion confinement that suppresses ion back‐diffusion and stabilizes channel doping, enabling robust nonvolatile synaptic memory, linear weight updates, and low‐energy operation.
Donghwa Lee   +9 more
wiley   +1 more source

Application of Ibuprofen Sodium Dihydrate for Thermochemical Energy Storage

open access: yesAdvanced Functional Materials, EarlyView.
Ibuprofen sodium dihydrate is introduced as a durable organic salt hydrate for low‐temperature thermochemical energy storage, operating within 60°C–110°C with high energy density. At the material level, it delivers ∼99.9% cycling efficiency over 150 cycles without deliquescence, enabled by a dual energy‐storage mechanism coupling dehydration and phase ...
Kavin Chakravarthy Thangaraj   +10 more
wiley   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

1H-NMR analysis of amino acid metabolism in cerebrospinal fluid of dogs with neurological distemper

open access: yesMacedonian Veterinary Review
Canine Distemper Virus (CDV) infection causes a multifocal demyelinating progressive disease within the central nervous system (CNS) that results in wide range of neurological symptoms.
Erdem Gülersoy   +6 more
doaj   +1 more source

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