Results 31 to 40 of about 223,391 (261)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

Nuclear magnetic resonance based structure of the protoberberine alkaloid coralyne and its self-association by spectroscopy techniques

open access: yesJournal of Pharmaceutical Analysis, 2019
Coralyne is an important alkaloid due to its anti-cancer and other medicinal properties. It targets DNA in cells and acts as human topoisomerase-I poison, telomerase inhibitor and nucleic acid intercalator.
Kumar Padmapriya, Ritu Barthwal
doaj   +1 more source

The NMR Spectra of Alkylbenzene

open access: yesThe Journal of the Society of Chemical Industry, Japan, 1967
23種類のモノアルキルベンゼンのNMRスペクトルから,プロトンのいろいろの型による化学シフトを測定した。側鎖アルキル基のα,β,γ位の炭素についているプロトンの化学シフトは,ベンゼン環の環電流によって顧著な影響を受け,αとβのプロトンは低磁場の方向に,γのプロトンは高磁場の方向にシフトする。これらの化学シフトの範囲を,側鎖アルキル基のプロトンの型および位置について詳細に決定した。その結果,ベンゼン環に近いところに枝分かれしたアルキル基があると,化学シフトに対する環電流の影響はより強くなることが認められた。これらのデーターを組合わせると,アルキルベンゼンの側鎖の詳細な構造について多くの情報を提供するであろう。
Kazuyoshi ITOH   +3 more
openaire   +2 more sources

The PRIMA Thesaurus for Materials Science and Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
The PRIMA Thesaurus is a structured vocabulary designed to improve how materials science data is described and shared. Developed with input from multiple experts, it enables clear documentation of research workflows, data exchange, and reuse across platforms.
Rossella Aversa   +8 more
wiley   +1 more source

Superlubricity and Corrosion Inhibition Properties of Solvate Ionic Liquids in Hybrid Carbon Fiber Reinforced Plastic–Steel Interfaces

open access: yesAdvanced Engineering Materials, EarlyView.
Solvate ionic liquids lubrication reduced the coefficient of friction by ∼60% compared to dry sliding, reaching steady‐state values as low as 0.04–0.05. Corrosion weight‐loss measurements in 1 M HCl further demonstrated significant inhibition behavior, with only 100 ppm of [Li(G3)][TFSI] (∼68.5 μL/L) reducing corrosion‐product weight loss by 63 ...
Sameh Dabees   +6 more
wiley   +1 more source

The Conformations of 1-Thiacyclooctan-3-One Dynamic Nuclear Magnetic Resonance and Force-Field Calculation [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 1995
The 1H and natural-abundance 13C-NMR spectra of 1-thiacyclooctan-3-one (1) have been measured from 25 to -100°C. Coalescence is observed in the 1H-NMR spectra of (1) at about -80°C, and attributed to ring inversion in a boat-chair conformation, which is ...
Mehran Ghiaci, Ahmad Reza Massah
doaj  

PFT-13C-Kernresonanz von Ribofuranosiden und Ribopyranosiden

open access: yesCHIMIA, 1972
The 13C-signals due to the carbon atoms of the anomeric furanoses and pyranoses in the pulse Fourier transform 13C-nmr spectra of D-ribose and 2-deoxy-D-ribose are assigned.
Eberhard Breitmaier   +2 more
doaj   +1 more source

Enhancing Low‐Temperature Performance of Sodium‐Ion Batteries via Anion‐Solvent Interactions

open access: yesAdvanced Functional Materials, EarlyView.
DOL is introduced into electrolytes as a co‐solvent, increasing slat solubility, ion conductivity, and the de‐solvent process, and forming an anion‐rich solvent shell due to its high interaction with anion. With the above virtues, the batteries using this electrolyte exhibit excellent cycling stability at low temperatures. Abstract Sodium‐ion batteries
Cheng Zheng   +7 more
wiley   +1 more source

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