Results 151 to 160 of about 159,141 (247)

Privacy and personalisation: predicting Parkinson's disease severity from real-world gait with federated learning. [PDF]

Front Aging Neurosci
Hinchliffe C, Hiden H, Alcock L, Lawson RA, Yarnall AJ, Rochester L, Del Din S, Watson P.   +7 more
europepmc   +1 more source

vEMRec: High‐Resolution Volume Electron Microscopy Reconstruction Based on Structure‐Preserving and High‐Fidelity 3D Alignment

Advanced Science, EarlyView.
vEMRec is a frequency‐adaptive computational framework for three‐dimensional alignment in volume electron microscopy. It integrates feature‐based rigid alignment with Gaussian filter‐guided elastic registration to correct rigid misalignments and nonlinear distortions while preserving structural fidelity.
Zhenbang Zhang, Hongjia Li, Zhongjun Yang, Zhiqiang Xu, Duanchen Sun, Xin Gao, Fa Zhang, Renmin Han   +7 more
wiley   +1 more source

Caveolar Endocytosis Governs Nanoneedle Transfection. [PDF]

ACS Nano
Sun N, Wang C, Wang Y, Edwards W, Dimitrievska M, Li Y, Vasovic N, McLennan S, Zhu H, Mäkilä E, Salonen J, Shen J, Peng Q, Scottà C, Lombardi G, Chiappini C.   +15 more
europepmc   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Pair invariant mass to isolate background in the search for the chiral magnetic effect in Au+Au collisions at $\sqrt{s_{_{\rm NN}}}$= 200 GeV [PDF]

, 2020
J. Adam, L. Adamczyk, J. R. Adams, J. K. Adkins, G. Agakishiev, M. M. Aggarwal, Z. Ahammed, I. Alekseev, D. M. Anderson, A. Aparin, E. C. Aschenauer, M. U. Ashraf, F. G. Atetalla, A. Attri, G. S. Averichev, V. Bairathi, K. N. Barish, A. Behera, R. Bellwied, A. Bhasin, J. Bielčík, J. Bielčíková, L. C. Bland, I. G. Bordyuzhin, J. D. Brandenburg, A. V. Brandin, J. M. Butterworth, H. Caines, M. CalderóndelaBarcaSánchez, D. Cebra, I. Chakaberia, P. Chaloupka, B. K. Chan, F-H. Chang, Z. Chang, N. Chankova-Bunzarova, A. Chatterjee, D. Chen, J. H. Chen, X. Chen, Z. Chen, J. Cheng, M. Cherney, M. Chevalier, S. Choudhury, W. Christie, X. Chu, H. J. Crawford, M. Csanád, M. Daugherity, T. G. Dedovich, I. Deppner, A. A. Derevschikov, L. Didenko, X. Dong, J. L. Drachenberg, J. C. Dunlop, T. Edmonds, N. Elsey, J. Engelage, G. Eppley, R. Esha, S. Esumi, O. Evdokimov, A. Ewigleben, O. Eyser, R. Fatemi, S. Fazio, P. Federic, J. Fedorišin, C. Feng, Y. Feng, P. Filip, E. Finch, Y. Fisyak, A. Francisco, Ł. Fulek, C. A. Gagliardi, T. Galatyuk, F. J. M. Geurts, S. M. Gibson, K. Gopal, D. Grosnick, W. Guryn, A. I. Hamad, A. Hamed, S. Harabasz, J. W. Harris, S. He, Wei He, X. H. He, S. Heppelmann, N. Herrmann, Eric A. Hoffman, L. Holub, Y. Hong, S. Horvat, Y. Hu, H. Z. Huang, S. Huang   +99 more
openalex  

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Beat-to-Beat QT Variability: A Population Study of the QT Variability Index Composition. [PDF]

Diagnostics (Basel)
Řehoř J, Helánová K, Šišáková M, Novotný T, Andršová I, Malik M.   +5 more
europepmc   +1 more source

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

Advanced Science, EarlyView.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang, Elsa Demes‐Causse, Xujian Li, Zhenhui Guo, Hanshu Zhao, Huairong Cao, Yajing Song, Lijun Mu, Kaikai Zhang, Jing Zhang, Zhongtao Jia, Lixing Yuan, Alexis De Angeli, Jingbo Zhang   +13 more
wiley   +1 more source

Relationship Between Heart Rate Variability and Sleep Among Girls and Boys With Abdominal Pain-Related Disorders of Gut-Brain Interaction. [PDF]

Neurogastroenterol Motil
Kamp KJ, Burr RL, Matherne CE, Simonds E, Murphy T, Heitkemper MM, Levy RL, Shulman RJ, van Tilburg MAL.   +8 more
europepmc   +1 more source

Unsupervised Hierarchical Symbolic Regression for Interpretable Property Modeling in Complex Multi‐Variable Systems

Advanced Science, EarlyView.
UHSR translates complex chemical behavior into clear and explainable equations. Applied to thin‐layer chromatography, it automatically uncovers the mathematical rules linking a molecule's structure to its polarity. This approach matches the accuracy of advanced AI while providing interpretable results, earning greater trust from chemists. The method is
Siyu Lou, Chengchun Liu, Dongxiao Zhang, Yuntian Chen, Fanyang Mo   +4 more
wiley   +1 more source