Results 171 to 180 of about 21,624,113 (316)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Haemophilia A in a Female German Shepherd With Homozygosity for the FVIII p.C567Y Variant in Exon 11 of the F8 Gene. [PDF]

Anim Genet
Brenig B, Pach S.
europepmc   +1 more source

References of references in Robotics. References of references in mobile robotics.

Journal of the Robotics Society of Japan, 1998
openaire   +2 more sources

Reference Notes (April 2005)

, 2005
Table of Contents includes: ACRL Conference Session Summary: Redesign Your Reference Desk: Get Rid of It!; Farewell Heidi Armstrong Temple!; Homeschoolers: Minitex Visits MACHE Conference; The EBSCO Business Searching Interface (BSI) in ELM is Now ...
Minitex Reference Outreach & Instruction
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

References of references in Robotics. References of references in teaching and planning.

Journal of the Robotics Society of Japan, 1998
openaire   +2 more sources

Reference Notes (May 2012)

, 2012
Table of Contents includes: ELM Database Renewed For Another Year; Interest in Pinerest?; Do You Have Klout? Marketing Technique Could Help Libraries; Google Knowledge Graph Is Boring; ELM Spotlight; May Is National Preservation Month: Discover America's
Minitex Reference Outreach & Instruction
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Authors' Reply: Beyond Visual Consensus: Tiered Reference Framework for AI Cystoscopy Studies. [PDF]

J Med Internet Res
Tsai CY, Huang SW.
europepmc   +1 more source

References of references in Robotics. References of references in kinematics and dynamics.

Journal of the Robotics Society of Japan, 1998
openaire   +2 more sources