Results 201 to 210 of about 3,785,737 (266)

Hybrid sequencing reveals incompleteness of the H37Rv reference genome and highlights lineage-specific genomic divergence in <i>Mycobacterium tuberculosis</i>. [PDF]

Microb Genom
Chen H, Li X, Chen R, Zhang M, Zhu Y, Wu K, Lu Y, Wang X, Che Y, Liu Z.   +9 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Sexual Orientation-Related Discrimination Among LGB+ Medical Students With Disabilities.

JAMA Netw Open
Sheets ZC, Nguyen M, Lopez JKM, Addams A, Moreland CJ, Boatright D, Meeks LM.   +6 more
europepmc   +1 more source

Wild Pedigree exploreR (wpeR): Streamlined Analysis and Visualization of Wild Pedigrees in Time and Space. [PDF]

Mol Ecol Resour
Simčič G, Skrbinšek T.
europepmc   +1 more source

Verification of harmonized reference intervals in Croatia: is it time for a change? [PDF]

Biochem Med (Zagreb)
Friščić I, Burazer I, Radeljak A, Perkov S, Kardum Paro MM.   +4 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Evaluation of Ceftriaxone Utilization in Three Regional Referral Hospitals in Uganda: A Prospective Multicentre Study. [PDF]

Infect Drug Resist
Munanura EI, Ndagire M, Kaggwa B, Ndagije HB, Kesi DN, Serwanga A, Rajab K, Kutyabami P, Kazinga C.   +8 more
europepmc   +1 more source

Angiotensin inhibitors during neoadjuvant chemotherapy improve esophageal squamous cell carcinoma outcomes. [PDF]

Ther Adv Med Oncol
Chen M, Huang Y, Liu F, Lin C, Zhang S, Zeng T, Yu J, Zheng B, Chen C.   +8 more
europepmc   +1 more source