Results 121 to 130 of about 21,624,113 (316)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reference Notes (July 2006)

, 2006
Table of Contents includes: Here We Go A Blogging: The New Minitex Reference Services Blog; Reinvented Reference - A Preconference; A Time to Build Up; My Time in NOLA - The Work that Needed to Get Done; Helping to Rebuild St.
Minitex Reference Outreach & Instruction
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reference Notes (September 2002)

, 2002
Table of Contents includes: OCLC's ArticleFirst; Gale's Discovering Collection; A New Look for Reference Notes; Information Bits.Minitex Reference Outreach & Instruction. (2002). Reference Notes (September 2002).
Minitex Reference Outreach & Instruction
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An Account of English YES/NO Interrogative Sentences within ARTEMIS

Revista de Lenguas para Fines Específicos, 2017
As stated in Periñán-Pascual and Arcas Túnez (2010, p. 2671) FunGramKB´s lexical and grammatical levels are grounded in sound linguistic theories, allowing the system to capture syntactic-semantic generalizations which are able to provide both ...
María Auxiliadora Martín Díaz
doaj  

Reference Notes (August 2009)

, 2009
Table of Contents includes: It's Back to School!; ELM Database Highlights: Back to School; Downloadable Slide; Presentation to Help; Promote ELM to Teachers; Spotlight on ELM - OAIster; MEMO Conference; Minitex Reference Fall Conference Calendar.Minitex ...
Minitex Reference Outreach & Instruction
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Reference Notes (October 2003)

, 2003
Table of Contents includes: Minneapolis Most Literate City; Virtual Reference Workshop; Informe! Mas de Cien Revistas y Periodicos; Question of the Month: New York Theater; How to WIN at "Career Pursuit"; Upcoming Teleconferences; Google Images via Gale ...
Minitex Reference Outreach & Instruction
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source