Results 121 to 130 of about 26,370,447 (260)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Reference Notes (December 2002)

open access: yes, 2002
Table of Contents includes: Virtual Reference Services Part 2: models of virtual reference; Ebooks: What's the Story?; Information Bits: Minitex Webinars are Here to Stay!Minitex Reference Outreach & Instruction. (2002).
Minitex Reference Outreach & Instruction
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Reference Notes (June 2001)

open access: yes, 2001
Table of Contents includes: Digital Reference Basics; Sources for Building Digital Reference Services; Real-life Examples of Digital Reference Service; Request for Assistance.Minitex Reference Outreach & Instruction. (2001).
Minitex Reference Outreach & Instruction
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

An Account of English YES/NO Interrogative Sentences within ARTEMIS

open access: yesRevista de Lenguas para Fines Específicos, 2017
As stated in Periñán-Pascual and Arcas Túnez (2010, p. 2671) FunGramKB´s lexical and grammatical levels are grounded in sound linguistic theories, allowing the system to capture syntactic-semantic generalizations which are able to provide both ...
María Auxiliadora Martín Díaz
doaj  

Professional Competencies for Reference and User Services Librarians 2017 Version

open access: yes, 2017
Replaced with a revised version in September 2025.As the professional organization for reference and user services, the Reference and Users Services Association (RUSA) has developed and updated a model statement of competencies essential for successful ...
RUSA Professional Competencies for Reference and User Services Librarians Task Force
core  

Online chat reference: Survey results from affiliates of two universities [PDF]

open access: yes, 2004
Reference librarians have converted a significant portion of library resources to electronic format and are now beginning to move the reference interview itself to the electronic environment.
Johnson, Corey, Johnson, Corey M.
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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