Results 101 to 110 of about 230,825 (293)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Comprehensive Performance Evaluation of Image Quality Assessment Algorithms

IEEE Access, 2019
Image quality assessment (IQA) algorithms aim to predict perceived image quality by human observers. Over the last two decades, a large amount of work has been carried out in the field.
Shahrukh Athar, Zhou Wang
doaj   +1 more source

Applicability Evaluation of Full-Reference Image Quality Assessment Methods for Computed Tomography Images. [PDF]

J Digit Imaging, 2023
Ohashi K, Nagatani Y, Yoshigoe M, Iwai K, Tsuchiya K, Hino A, Kida Y, Yamazaki A, Ishida T.   +8 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

An Optimization-Based Family of Predictive, Fusion-Based Models for Full-Reference Image Quality Assessment. [PDF]

J Imaging, 2023
Varga D.
europepmc   +1 more source

No-Reference Hyperspectral Image Quality Assessment via Quality-Sensitive Features Learning

, 2017
Assessing the quality of a reconstructed hyperspectral image (HSI) is of significance for restoration and super-resolution. Current image quality assessment methods such as peak signal-noise-ratio require the availability of pristine reference image ...
Jingxiang Yang, Yongqiang Zhao, Chen Yi, Jonathan Cheung-Wai Chan   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

No-reference synthetic image quality assessment with convolutional neural network and local image saliency

Computational Visual Media, 2019
Depth-image-based rendering (DIBR) is widely used in 3DTV, free-viewpoint video, and interactive 3D graphics applications. Typically, synthetic images generated by DIBR-based systems incorporate various distortions, particularly geometric distortions ...
Xiaochuan Wang, Xiaohui Liang, Bailin Yang, Frederick W. B. Li   +3 more
doaj   +1 more source