Results 191 to 200 of about 222,730 (255)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Pediatric Diagnostic Reference Levels for Chest X-Rays in the Northern Cape Province of South Africa: A Descriptive Study. [PDF]

Health Sci Rep
Lackay OL, Horn-Lodewyk J, Muller H.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Coronary stenosis assessment: AI-based CT quantification, visual analysis of invasive angiography, and quantitative coronary angiography. [PDF]

Insights Imaging
Yu L, Yuan M, Dai X, Yu Y, Yuan J, Zheng C, Xu L, Liu T, Zhang J.   +8 more
europepmc   +1 more source

A Fully Automated Pipeline for Vertebral Structural Assessment From Medical Images. Application Under Metastatic Conditions. [PDF]

Int J Numer Method Biomed Eng
Gandia-Vañó B, Navarro-Jiménez JM, Ródenas JJ, Arana E, Nadal E.   +4 more
europepmc   +1 more source

Q.Clear reconstruction shortening the scanning time for ¹¹C-CFT brain PET/MR imaging. [PDF]

EJNMMI Phys
Chen L, Gong W, Wang D, Long H, Li X, Xia R, Yao Y, Zhou W, Zhou W, Chen X.   +9 more
europepmc   +1 more source

Fully automated artificial intelligence-based echocardiographic analysis substantially reduces workflow time while preserving measurement accuracy: a pilot study. [PDF]

J Cardiovasc Imaging
Sun J, Yoon YE, Lee J, Lee G, Bak M, Park J, Choi HM, Hwang IC, Cho GY.   +8 more
europepmc   +1 more source

Data annotation and its evaluation in artificial intelligence-based anatomy recognition for ultrasound-guided regional anesthesia: a clinical perspective. [PDF]

Front Med (Lausanne)
Delvaux BV, Elmaleh Y, Chuan A, Sia AT, Gupta RK, Schroeder KM, Guessous K, Bowness JS.   +7 more
europepmc   +1 more source

Development and preliminary clinical validation of a mobile health application for pressure injury staging in ICU patients. [PDF]

Front Med (Lausanne)
Sheng H, Hu C, Zhang D, Zhu Z, Xu D.
europepmc   +1 more source