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State of the Art: No-Reflow Phenomenon.
Cardiology clinics, 2020Primary percutaneous coronary intervention is the preferred reperfusion strategy for the management of acute ST-segment elevation myocardial infarction. No reflow is characterized by the inadequate myocardial perfusion of a given segment without angiographic evidence of persistent mechanical obstruction of epicardial vessels.
Caiazzo, G +7 more
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The objective of this study was to investigate the impact of no-reflow phenomenon on 5-year mortality among patients with acute ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PCI).
Klaus Tiroch +2 more
exaly +3 more sources
Current Treatment Options in Cardiovascular Medicine, 2005
No-reflow occurs in up to one third of patients with acute myocardial infarction during acute percutaneous intervention, and occasionally during elective interventions, particularly vein graft intervention. Multiple intracoronary medications will restore flow in most cases.
Shereif H, Rezkalla, Robert A, Kloner
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No-reflow occurs in up to one third of patients with acute myocardial infarction during acute percutaneous intervention, and occasionally during elective interventions, particularly vein graft intervention. Multiple intracoronary medications will restore flow in most cases.
Shereif H, Rezkalla, Robert A, Kloner
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Management of the no-reflow phenomenon
Pharmacology & Therapeutics, 2011The lack of reperfusion of myocardium after prolonged ischaemia that may occur despite opening of the infarct-related artery is termed "no reflow". No reflow or slow flow occurs in 3-4% of all percutaneous coronary interventions, and is most common after emergency revascularization for acute myocardial infarction.
Michelle J, Butler +4 more
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The No-Reflow Phenomenon in the Coronary Circulation
Cardiovascular & Hematological Agents in Medicinal Chemistry, 2009The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries.
Thomas J, Kiernan +7 more
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Pathophysiology of the no-reflow phenomenon
Acute Cardiac Care, 2009The no-reflow phenomenon occurs in about one third of the patients treated with primary PCI for acute ST segment elevation myocardial infarction. Our understanding of its pathophysiology has expanded considerably: in addition of the effect of prolonged ischaemia also reperfusion injury contributes significantly to the microvascular damage in the ...
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2016
No-reflow describes a condition in which myocardial blood flow is reduced after a coronary intervention, despite angiographically patent coronary arteries. It is diagnosed by reduced epicardial blood flow in the presence of a seemingly patent coronary artery, however its incidence is thought to be higher than is estimated by clinical judgment or ...
Ismail Dogu Kilic +3 more
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No-reflow describes a condition in which myocardial blood flow is reduced after a coronary intervention, despite angiographically patent coronary arteries. It is diagnosed by reduced epicardial blood flow in the presence of a seemingly patent coronary artery, however its incidence is thought to be higher than is estimated by clinical judgment or ...
Ismail Dogu Kilic +3 more
openaire +1 more source
1988
The no-reflow phenomenon following a severe ischemic episode was first described in the brain [1] and subsequently has been observed in other organs including the kidney [2] and the heart [3]. In the brain edema and increased intracranial pressure inside of the rigid skull have been shown to limit reflow.
C. E. Ganote, R. S. Heide
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The no-reflow phenomenon following a severe ischemic episode was first described in the brain [1] and subsequently has been observed in other organs including the kidney [2] and the heart [3]. In the brain edema and increased intracranial pressure inside of the rigid skull have been shown to limit reflow.
C. E. Ganote, R. S. Heide
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2005
A 53-year-old man presented to the emergency room with an acute inferolateral myocardial infarction (MI) of 2 hours duration. Urgent coronary angiography showed minor obstructive disease in the left coronary system and a 100% thrombotic occlusion in the mid segment of a large right coronary artery (Figure 8-1A).
H. M. Omar Farouque, David P. Lee
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A 53-year-old man presented to the emergency room with an acute inferolateral myocardial infarction (MI) of 2 hours duration. Urgent coronary angiography showed minor obstructive disease in the left coronary system and a 100% thrombotic occlusion in the mid segment of a large right coronary artery (Figure 8-1A).
H. M. Omar Farouque, David P. Lee
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2017
Despite outstanding achievements in the last decades in the treatment of coronary artery disease and especially acute myocardial infarction, mortality and morbidity on follow-up have remained high. High morbidity is partly a result of the no-reflow phenomenon, which is the inability to reperfuse a previously ischemic region despite achieved patency of ...
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Despite outstanding achievements in the last decades in the treatment of coronary artery disease and especially acute myocardial infarction, mortality and morbidity on follow-up have remained high. High morbidity is partly a result of the no-reflow phenomenon, which is the inability to reperfuse a previously ischemic region despite achieved patency of ...
openaire +1 more source

