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Pathophysiology of the no-reflow phenomenon
Acute Cardiac Care, 2009The no-reflow phenomenon occurs in about one third of the patients treated with primary PCI for acute ST segment elevation myocardial infarction. Our understanding of its pathophysiology has expanded considerably: in addition of the effect of prolonged ischaemia also reperfusion injury contributes significantly to the microvascular damage in the ...
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1988
The no-reflow phenomenon following a severe ischemic episode was first described in the brain [1] and subsequently has been observed in other organs including the kidney [2] and the heart [3]. In the brain edema and increased intracranial pressure inside of the rigid skull have been shown to limit reflow.
C. E. Ganote, R. S. Heide
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The no-reflow phenomenon following a severe ischemic episode was first described in the brain [1] and subsequently has been observed in other organs including the kidney [2] and the heart [3]. In the brain edema and increased intracranial pressure inside of the rigid skull have been shown to limit reflow.
C. E. Ganote, R. S. Heide
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The No-Reflow Phenomenon in the Coronary Circulation
Cardiovascular & Hematological Agents in Medicinal Chemistry, 2009The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries.
Thomas J, Kiernan +7 more
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The no-reflow phenomenon in the young and in the elderly
International Journal of Cardiology, 2016The objectives of this study were to evaluate the incidence of no-reflow as independent predictor of adverse events and to assess whether baseline pre-procedural treatment options may affect clinical outcomes.Data were derived from the ISACS-TC registry (NCT01218776) from October 2010 to January 2015.
CENKO, EDINA +13 more
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2005
A 53-year-old man presented to the emergency room with an acute inferolateral myocardial infarction (MI) of 2 hours duration. Urgent coronary angiography showed minor obstructive disease in the left coronary system and a 100% thrombotic occlusion in the mid segment of a large right coronary artery (Figure 8-1A).
H. M. Omar Farouque, David P. Lee
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A 53-year-old man presented to the emergency room with an acute inferolateral myocardial infarction (MI) of 2 hours duration. Urgent coronary angiography showed minor obstructive disease in the left coronary system and a 100% thrombotic occlusion in the mid segment of a large right coronary artery (Figure 8-1A).
H. M. Omar Farouque, David P. Lee
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Novel insights into an “old” phenomenon: the no reflow
International Journal of Cardiology, 2015Coronary artery diseases and particularly acute myocardial infarction are the leading causes of mortality and morbidity in western countries. Despite the achievements of the last decades with the advent of double antiplatelet therapy, new antithrombotics and reperfusion strategies (either pharmacological or mechanical), many patients still have adverse
Alessandro Durante, Paolo G. Camici
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1975
The no-reflow phenomenon (NRP) was demonstrated in the rabbit brain by Ames et al. (1). After earlier interruption of the basilar artery a pressure cuff around the neck was inflated to 350 mm Hg to ensure cerebral circulatory arrest while ventilation was maintained mechanically in the paralyzed animal.
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The no-reflow phenomenon (NRP) was demonstrated in the rabbit brain by Ames et al. (1). After earlier interruption of the basilar artery a pressure cuff around the neck was inflated to 350 mm Hg to ensure cerebral circulatory arrest while ventilation was maintained mechanically in the paralyzed animal.
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2017
Despite outstanding achievements in the last decades in the treatment of coronary artery disease and especially acute myocardial infarction, mortality and morbidity on follow-up have remained high. High morbidity is partly a result of the no-reflow phenomenon, which is the inability to reperfuse a previously ischemic region despite achieved patency of ...
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Despite outstanding achievements in the last decades in the treatment of coronary artery disease and especially acute myocardial infarction, mortality and morbidity on follow-up have remained high. High morbidity is partly a result of the no-reflow phenomenon, which is the inability to reperfuse a previously ischemic region despite achieved patency of ...
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The no-reflow phenomenon is a post-mortem artifact
Acta Neurochirurgica, 1992Post-ischemic reperfusion impairment, ("no-reflow phenomenon"), was studied in rats subjected to 8-30 minutes of global brain ischemia. During ischemia, rapid and complete loss of cerebral blood flow, EEG and 31P-high energy phosphates (ATP/PCr) was observed. Brain intravascular perfusion defects were examined by injecting carbon black intravenously in
de la Torre, J. C. +4 more
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THE NO-REFLOW PHENOMENON IN EXPERIMENTAL FREE FLAPS
Plastic and Reconstructive Surgery, 1978The no-reflow phenomenon was studied following reconstitution of blood flow by microvascular anastomosis in an ischemic and denervated free epigastric flap in the rabbit. Microscopic, histological, angiographic, and hematological studies demonstrated the progressive nature of this obstruction to the peripheral blood flow after increasing periods of ...
J W, May +3 more
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