Results 201 to 210 of about 6,752,497 (289)

Comparative Meta‐Analysis of Antimicrobial Peptides in Aquatic and Terrestrial Livestock Species

open access: yesAnimal Research and One Health, EarlyView.
A global meta‐analysis of 58 studies (926 effect sizes and 29 species across five taxa) revealed that dietary antimicrobial peptides generally improve growth performance, blood metabolites, and immune responses. The greatest benefits were observed in omnivorous livestock, such as pigs and chickens. Dose‐duration effects were evident. An optimal outcome
Lily Liu   +4 more
wiley   +1 more source

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

open access: yesAnimal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao   +12 more
wiley   +1 more source

Pediatric Climbers Experience More Upper Extremity Injuries, Geriatric Climbers More Lower Extremity Injuries, and Increased Shoulder Trauma Associated With Male Individuals in an Emergency Department Analysis of Rock Climbing–Associated Musculoskeletal Injuries

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To analyze epidemiologic trends, injury prevalence, and mechanisms of injury associated with rock climbing. Methods The National Electronic Injury Surveillance System, a public emergency department database, was queried for rock climbing–related injuries from 2014 to 2023. Data extracted included demographics, anatomic region injured, diagnosis,
Titan Z. Alexio   +6 more
wiley   +1 more source

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova   +9 more
wiley   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila   +12 more
wiley   +1 more source

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