Results 241 to 250 of about 28,928,863 (316)

A Study on the Depressive Symptoms and Life Satisfaction Among Middle-Aged and Older Adults in China Based on CHARLS 2020 Data. [PDF]

Behav Sci (Basel)
Wang S, Shirayama Y, Ahmad I, Okamoto M, Yuasa M.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Maternal Body Mass Index, Gestational Weight Gain, and Cardiovascular Disease in Offspring.

JAMA Netw Open
Wang H, Möller J, Liang Y, Janszky I, László KD.   +4 more
europepmc   +1 more source

FANTASIA suite: a reproducible and configurable framework for embedding-based functional annotation of proteins. [PDF]

NAR Genom Bioinform
Pérez-Canales FM, Domínguez-Rodríguez À, Carbonetto B, Fernández R, Cases I, Rojas AM.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Impact of Laboratory Data Integration into Outpatient Prescriptions on Community Pharmacist Feedback and Physician Responses: A Single-Center Retrospective Study. [PDF]

Risk Manag Healthc Policy
Motoki T, Tanaka H, Tai T, Yamaguchi K, Kosaka S, Mino Y.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Temporal changes and reference values for adolescent handgrip strength in the Republic of Korea: A 9-year analysis of the KNHANES cohort. [PDF]

PLoS One
Grgic J, Wazny VK, Varovic D.
europepmc   +1 more source

References of references in Robotics. References of references in multi-fingered hand.

Journal of the Robotics Society of Japan, 1998
openaire   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source