Results 321 to 330 of about 346,633 (388)

A comprehensive overview of yeast libraries and their role in advancing cell biology

open access: yesThe FEBS Journal, EarlyView.
Systematic, genome‐wide yeast mutant libraries have revolutionized systems and cell biology. By allowing high‐throughput interrogation of every gene and protein, they have defined gene essentiality, charted protein localization, illuminated function, mapped interactions, and more.
Din Baruch, Maya Schuldiner, Ofir Klein
wiley   +1 more source

Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation

open access: yesThe FEBS Journal, EarlyView.
Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev   +2 more
wiley   +1 more source

The Nature of Christian Doctrine: A Conversation with My Critics

open access: yesInternational Journal of Systematic Theology, EarlyView.
Abstract This article opens with a brief account of the six main themes of The Nature of Christian Doctrine, noting in particular the role of the early church as an ‘epistemic community’ of knowledge production, and the significant and helpful parallels between the modern scientific tool of ‘inference to the best explanation’ and early Christian ...
Alister E. McGrath
wiley   +1 more source

Boniteza's Arts Chair, Pedagogical Curatorial Practices with Contemporary Artists as Arts‐Based Educational Research

open access: yesInternational Journal of Art &Design Education, EarlyView.
Abstract This article puts forward a new methodology in artistic education. It is based on scientific utopia as it aims for the implementation in schools of the cátedras de la Boniteza (the Boniteza's Art Chair), where an inhabiting artist changes the institution from within through the development of quality art projects.
José María Mesías‐Lema
wiley   +1 more source

Macrocyclic geminal diols: synthesis, structures, stability and photophysical properties. [PDF]

open access: yesChem Sci
Zou B   +10 more
europepmc   +1 more source
Some of the next articles are maybe not open access.

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Nobel Prize paradox: Nobel Prize, not a noble prize

Revista Clínica Española (English Edition)
The Nobel Prize is one of the most sought-after awards in science and society. However, its reputation is not without complexities, including constraints on laureates and biases in nominations. Navigating the delicate balance between recognition and the tangible impacts of awarded contributions should offer insight into the Prize's significance beyond ...
K. Moustafa
openaire   +3 more sources

Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

Angewandte Chemie - International Edition, 2012
Matthew O Kitching   +2 more
exaly   +2 more sources

The Nobel Prize in Chemistry 2022: Fulfilling Demanding Applications with Simple Reactions.

ACS Chemical Biology, 2022
The Nobel Prize in Chemistry 2022 was awarded jointly to Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless "for the development of click chemistry and bioorthogonal chemistry". Such rapid, selective, and nontoxic covalent reactions that link two
Peng Wu
semanticscholar   +1 more source

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