Results 111 to 120 of about 3,020 (254)

From settler gardens to digital naturalists: human aesthetic preferences and land use changes facilitate the biogeographical expansion of a wild plant–virus interaction

PLANTS, PEOPLE, PLANET, EarlyView.
Anthropogenic facilitation of wild plants based on aesthetic preferences for particular traits can change the biogeography and ecology of natural communities. We use a mixed‐methods socioecological approach to characterize the ways in which humans interact with a common, widely distributed plant and a generalist viral symbiont that induces an ...
Elizabeth M. Lombardi, Jasmine S. Peters, Juan Pablo Jordán, Alison G. Power   +3 more
wiley   +1 more source

Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application

Responsive Materials, EarlyView.
Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li, Xue Wu, Zekun Yan, Jun Wu, Caishi Huang, Songnan Qu   +5 more
wiley   +1 more source

A Hero's Journey to Systemic Change: Developing Expertise in Agricultural Development

Sustainable Development, EarlyView.
ABSTRACT Experts in rural development and agrarian change wield considerable influence over programme design and delivery, directing resources and shaping trajectories towards the Sustainable Development Goals (SDGs). Yet the pathways through which such expertise develops remain under‐examined. This study examines the journey to expertise among experts
Kirt Hainzer, Caitlin Finlayson, Nicholas Harrigan, Andrew McGregor, Katharine McKinnon, Van Touch, Ariane Utomo, Brian R. Cook   +7 more
wiley   +1 more source

Does Economic Growth Drive Equitable Water and Sanitation Access? Assessing Inequality Reduction Across 64 Nations

Sustainable Development, EarlyView.
ABSTRACT This article examines whether economic growth reduces inequalities in access to water and sanitation across 64 countries over an average period of 13.5 years. Drawing on disaggregated data by income quintiles and rural–urban location, and employing ordinary least squares (OLS), two‐stage least squares (2SLS), and Seemingly Unrelated Regression
Marcos García‐López, Samara López‐Ruiz, Gabriela Cuadrado‐Quesada   +2 more
wiley   +1 more source

Sustainability Assessment: The Role of Entropy‐Based Indicators for Reconnecting Human' Subjectivity and Civilization With Natural Tendency of Ecosystems

Sustainable Development, EarlyView.
ABSTRACT Sustainability represents a complex issue in which scientific knowledge inevitably coexists with the subjective perception of humans in its turn influenced by civilization, cultural but also unconscious aspects. These results emerge with evidence from a critical analysis of the main definitions of sustainability delivered by credited entities (
Francesco Di Maria, Hamid Safarzadeh
wiley   +1 more source

Ultrasensitive MicroRNA Detection Combining Reduced Graphene Oxide Electrolyte‐Gated Transistors and Machine Learning

Small, EarlyView.
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo, Gabrielle Coelho Lelis, Maria Luisa Braunger, Stefano Casalini, Yasmin Watanabe, Gabriel Ravanhani Schleder, Wilson Tiago Fonseca, Rafael Furlan de Oliveira   +7 more
wiley   +1 more source

Migrating bards: Writers’ burdens and a writers’ body in Nigeria at the turn of the century

Tydskrif vir Letterkunde, 2018
Wole Soyinka’s 1986 Nobel Prize for literature was received as a well deserved international recognition not only of the distinction of Soyinka’s sustained output but also as a tribute to Nigerian and African literature in general. However, given decades
Isidore Diala
doaj  

Heroes in endocrinology: Nobel Prizes. [PDF]

Endocr Connect, 2014
de Herder WW.
europepmc   +1 more source

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

Smart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu, Sen Cai, Yanyan Pan, Heshuang Wang, Fengwu Zhang, Aiyu Ma, Shixuan Lv, Xiuhan Guo, Shisheng Wang, Qiling Song, Chunyan Ma, Shuai Wang, Li Zhang, Jian Wang, Qingwei Meng, Yueqing Li   +15 more
wiley   +1 more source