Results 151 to 160 of about 90,745 (245)
Questioning the Experimental Protocol in Two Nobel Prizes
International audienceFor discussions in the scientific community, we question the Post-Selection protocols (also known as p-hacking) in works that received the Nobel Prize in Physics 2024 and the Nobel Prize in Chemistry 2024, as well as the current ...
Schmidt, Colin, T. +3 more
core +1 more source
Seeded Growth of Plasmonic Core‐Shell NU‐1000 NanoMOFs With Intracellular Optical Readout
Small, EarlyView.Seed‐mediated growth yields plasmonic core‐shell nanocomposites by encapsulating gold nanoparticles within NU‐1000 nanoMOFs, preserving morphology and optical response. The materials exhibit tunable photoluminescence quenching, efficient photothermal heating, and SERS activity.
Manuel Ceballos +9 more
wiley +1 more source
Smart Molecules, EarlyView.Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu +15 more
wiley +1 more source
Halted medical education in Korea amid Nobel Prizes in deep learning and machine learning research, tribute to a leader of Ewha Womans University College of Medicine, and highlights from this issue. [PDF]
Ewha Med JHuh S.
europepmc +1 more source
Smart Molecules, EarlyView.A pKa‐engineered near‐infrared fluorescent probe (DCM‐2F‐B) enables sensitive imaging of oxidative stress in atherosclerotic plaques. Difluoro substitution lowers the phenolic hydroxyl pKa from 9.1 to 6.0, achieving near‐complete ionization at physiological pH.
Qianqian Yu +10 more
wiley +1 more source
Accelerating innovation with prize rewards: History and typology of technology prizes and a new contest design for innovation in African agriculture [PDF]
"This paper describes how governments and philanthropic donors could drive innovation through a new kind of technology contest. We begin by reviewing the history of technology prizes, which operate alongside private intellectual property rights and ...
Masters, William A., Delbecq, Benoit
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Southern Economic Journal, EarlyView.ABSTRACT The Allais Paradox is often attributed to the strong attraction of a certain option that avoids a downside risk, i.e., a small chance of a low payoff. In contrast, there is clear evidence from laboratory and field data that people are attracted to the upside risk of obtaining a relatively high payoff.
Irene Comeig, Charles Holt
wiley +1 more source
Elisabeth Crawford, The beginnings of the Nobel institution. The Science Prizes, 1901-1915
, 1986 Elisabeth Crawford, The beginnings of the Nobel institution. The Science Prizes, 1901-1915. In: Revue d'histoire des sciences, tome 39, n°1, 1986.
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Five Decades of Dispute: A Triptych. E. J. Corey
The Chemical Record, EarlyView.In his 2004 Priestley Medal address, E. J. Corey stated, “On May 4, 1964, I suggested to my colleague R. B. Woodward a simple explanation involving the symmetry of the perturbed (HOMO) molecular orbitals for the stereoselective cyclobutene/1,3‐butadiene and 1,3,5‐hexatriene/cyclohexadiene conversions that provided the basis for the further development ...
Jeffrey I. Seeman
wiley +1 more source
Oxaziridines: Versatile Reagents in Modern Organic Synthesis
The Chemical Record, EarlyView.Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra +2 more
wiley +1 more source