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The role of pain expectancy and its confidence in placebo hypoalgesia and nocebo hyperalgesia.
PainPlacebo hypoalgesia and nocebo hyperalgesia, which exemplify the impact of expectations on pain, have recently been conceptualised as Bayesian inferential processes, yet empirical evidence remains limited.
E. Camerone, G. Tosi, Daniele Romano
semanticscholar +1 more source
2008
There are four general reasons for clinical improvement in a patient’s condition: (1) natural history of the disease; (2) specific effects of the treatment; (3) regression to the mean; and (4) nonspecific effects of the treatment that are attributable to factors other than the specific active components. The latter effect is included under the heading ‘
Stephen P. Glasser, William H. Frishman
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There are four general reasons for clinical improvement in a patient’s condition: (1) natural history of the disease; (2) specific effects of the treatment; (3) regression to the mean; and (4) nonspecific effects of the treatment that are attributable to factors other than the specific active components. The latter effect is included under the heading ‘
Stephen P. Glasser, William H. Frishman
openaire +2 more sources
Visual placebo and nocebo effects.
Journal of PhysiologyPlacebo and nocebo effects modulate symptom perception through expectations and learning processes in various domains. Predominantly, their impact has been investigated on pain and physical performance.
Alessandro Piedimonte +6 more
semanticscholar +1 more source
2016
A placebo effect is the effect that follows the administration of a placebo, that is, of an inert pharmacological or physical treatment. It is important to point out that the inert treatment is given along with contextual stimuli, for example, verbal suggestions of clinical improvement that make the patient believe that the treatment is real and ...
Amanzio, Martina +2 more
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A placebo effect is the effect that follows the administration of a placebo, that is, of an inert pharmacological or physical treatment. It is important to point out that the inert treatment is given along with contextual stimuli, for example, verbal suggestions of clinical improvement that make the patient believe that the treatment is real and ...
Amanzio, Martina +2 more
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Mechanisms of Placebo and Nocebo
2019Placebo effects can be conceptualized as the beneficial effects triggered by the psychosocial treatment context. The nocebo effect is its negative counterpart. Over the last 30 years, the knowledge of placebo and nocebo effects has increased substantially.
Elisa Carlino +2 more
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Annual Review of Psychology, 2019
Placebo effects constitute a major part of treatment success in medical interventions. The nocebo effect also has a major impact, as it accounts for a significant proportion of the reported side effects for many treatments.
K. Petrie, W. Rief
semanticscholar +1 more source
Placebo effects constitute a major part of treatment success in medical interventions. The nocebo effect also has a major impact, as it accounts for a significant proportion of the reported side effects for many treatments.
K. Petrie, W. Rief
semanticscholar +1 more source
Pain and the Placebo/Nocebo Effect
2011In the last 20 years, placebo and nocebo research has provided scientific ground for a phenomenon once believed to be only patient mystification, or at best a variable to control in clinical trials. Neurochemical, pharmacological and neuroimaging studies are elucidating the mechanisms by which the activation of identifiable neural pathways produces ...
POLLO, Antonella, BENEDETTI, Fabrizio
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Placebo and Nocebo Effects in Itch and Pain
2014Physical complaints, such as pain, can be effectively altered by placebo and nocebo effects due to induction of positive or negative expectations. While verbal suggestion and conditioning are recognized as playing a key role in placebo and nocebo effects on pain, these mechanisms have barely been investigated with regard to other somatosensory ...
Danielle J. P. Bartels +5 more
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Placebo, Nocebo, and Learning Mechanisms
2014Recent substantial laboratory and theoretical research hints for different learning mechanisms regulating the formation of placebo and nocebo responses. Moreover, psychological and biological variants may play a role as modulators of learning mechanisms underlying placebo and nocebo responses. In this chapter, we present pioneering and recent human and
openaire +3 more sources
2019
Nocebo refers to adverse events (AEs) related to negative expectations that medical treatment will likely harm instead of heal and affects significantly adherence and treatment outcome. It varies considerably among neurological conditions but can be assessed in placebo-controlled clinical trials (RCTs) by investigating the AEs observed in patients ...
Christina I. Deligianni +1 more
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Nocebo refers to adverse events (AEs) related to negative expectations that medical treatment will likely harm instead of heal and affects significantly adherence and treatment outcome. It varies considerably among neurological conditions but can be assessed in placebo-controlled clinical trials (RCTs) by investigating the AEs observed in patients ...
Christina I. Deligianni +1 more
openaire +2 more sources