Results 181 to 190 of about 214,955 (346)

Opicapone in Parkinson's Disease on Levodopa‐Carbidopa Intestinal Gel Treatment: A Pilot, Randomized Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Levodopa‐carbidopa intestinal gel infusion (LCIG) is an effective therapy for advanced Parkinson's disease (PD). Opicapone (OPC) is an enzyme inhibitor that enhances the bioavailability of levodopa in the brain. Objectives This study evaluates the effect of Opicapone addition in PD‐LCIG patients, assessing its impact on motor ...
Fabiana Colucci   +9 more
wiley   +1 more source

Serum Anti-γG Globulin Factors in Paroxysmal Nocturnal Hemoglobinuria [PDF]

open access: bronze, 1966
Manuel E. Kaplan   +3 more
openalex   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

AN EXAMPLE OF A NOCTURNAL LOW-LEVEL JET STREAM [PDF]

open access: bronze, 1962
J. R. Gerhardt
openalex   +1 more source

Microstructural Changes in the Tuberal Hypothalamus Correlate with Daytime Sleepiness in Lewy Body Disorders

open access: yesMovement Disorders, EarlyView.
Abstract Background Excessive daytime sleepiness (EDS) is a disabling symptom of Lewy body disorders (LBD). The hypothalamus is a key sleep–wake regulator and is involved in Lewy pathology, but its contribution to EDS in LBD remains unclear. Objectives To use diffusion‐weighted magnetic resonance imaging (MRI) to detect hypothalamic microstructure and ...
Jesse S. Cohen   +8 more
wiley   +1 more source

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