Results 141 to 150 of about 313,820 (353)

On a pencil of nodal cubics. Second paper [PDF]

open access: gold, 1920
Nathan Altshiller‐Court
openalex   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

open access: yesAdvanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao   +14 more
wiley   +1 more source

Re‐Purposing a Modular Origami Manipulator Into an Adaptive Physical Computer for Machine Learning and Robotic Perception

open access: yesAdvanced Science, EarlyView.
Reservoir computing in the physical domain promises an alternative, more energy‐efficient approach to machine learning. However, the correlation between mechanical design and computing power remains elusive. This study sheds light on this gap by repurposing a meta‐stable modular origami manipulator into an adaptive computing kernel that can perform ...
Jun Wang, Suyi Li
wiley   +1 more source

Intravenous iRGD‐Guided, RBC‐Membrane Camouflaged Lactococcus Lactis Remodels Cold NSCLC and Enhances PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study presents an engineered probiotic platform, iRGD‐mRBC@FOLactis, combining red blood cell membrane cloaking and tumor‐penetrating peptide iRGD for enhanced PD‐1 blockade. The platform improves tumor targeting, immune cell activation and therapeutic efficacy in lung cancer, demonstrating significant promise in overcoming PD‐1/PD‐L1 therapy ...
Chen Chen   +9 more
wiley   +1 more source

Experiencia vivida de mujeres durante su control prenatal en una zona rural

open access: yesRevista Ciencias de la Salud
Introducción: El control prenatal son acciones que involucra múltiples visitas de la mujer embarazada a instituciones de salud, para llevar a cabo la vigilancia, evolución del embarazo, así como detectar riesgos, prevenir complicaciones, preparar a la ...
Andrea Tagle Calvario   +4 more
doaj   +1 more source

Revealing the Character of Coordination Bonding in 2D Metal–Organic Frameworks

open access: yesAdvanced Science, EarlyView.
Photoemission‐derived momentum maps and density functional theory calculations show the re‐appearance of frontier molecular orbital patterns at two distinct binding energies, a result of the formation of bonding and antibonding states below the Fermi edge from covalent hybridisation with the metal centres.
Dominik Brandstetter   +7 more
wiley   +1 more source

Bioethical and Human Right Considerations during COVID-19 Pandemic Period: Reflections of Integrated Oncology Clinical Services from India

open access: yesIndian Journal of Medical and Paediatric Oncology
Ever since the outbreak of COVID-19, the global health care systems are overwhelmed to cope up with the rapidly evolving disease paradigm through implementation of action plans at societal and medical domains.
Lal P. Madathil   +8 more
doaj   +1 more source

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