Results 61 to 70 of about 321,091 (361)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Escribir lo real: del giro ontológico al giro práctico

Revista nuestrAmérica
En la actualidad hay toda una serie de interrogantes y discusiones suscitadas en torno a lo real: ¿Qué es real? ¿Lo real está perdido? ¿Cómo nos afecta lo real?
Roque Farrán
doaj   +1 more source

A cross-sectional study of extent and causes of interruption of treatment of tuberculosis in a tuberculosis unit of Purba Bardhaman district of West Bengal, India

Asian Journal of Medical Sciences, 2023
Background: Tuberculosis (TB) is a communicable disease which requires prolonged treatment and having both medical and social dimensions. Adherence to treatment is very important issue in successful treatment of TB.
Chinmay Nandi , Kaushik Mitra , Dipankar Bhaumik   +2 more
doaj   +1 more source

Diagnostic Utility of Testing for Novel Murine Autoantibodies for Sjögren's Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, Accepted Article.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

Geometric Optimization and Mechanical Performance Enhancement of Auxetic Structures for High‐Impact Applications Through Fused Deposition Modeling

Advanced Engineering Materials, EarlyView.
This study explores the mechanical performance of three auxetic structures, identifying a re‐entrant‐star hybrid as the most effective for impact absorption. Finite element simulations and experiments demonstrate significant gains in energy absorption and flexural strength after geometric optimization. This study investigates the mechanical performance
Malik Hassan, Manjusri Misra, Alexander Bardelcik, Stefano Gregori, Amar K. Mohanty   +4 more
wiley   +1 more source

SIU-ICUD: Management of Lymph Node–Positive Prostate Cancer

Société Internationale d’Urologie Journal
Background/Objectives: The management of localized prostate cancer with regional lymph node involvement (N1M0) presents significant clinical challenges.
Haitham Shaheen, Mack Roach, Eman Essam Elsemary   +2 more
doaj   +1 more source

Nodal rings and drumhead surface states in phononic crystals

Nature Communications, 2019
Three-dimensional topological nodal lines, the touching curves of two bands in momentum space, which give rise to drumhead surface states, provide an opportunity to explore a variety of exotic phenomena.
Weiyin Deng, Jiuyang Lu, Feng Li, Xueqin Huang, Mou Yan, Jiahong Ma, Zhengyou Liu   +6 more
semanticscholar   +1 more source

Nodal-link semimetals [PDF]

, 2017
In topological semimetals, the valance band and conduction band meet at zero-dimensional nodal points or one-dimensional nodal rings, which are protected by band topology and symmetries. In this Rapid Communication, we introduce ``nodal-link semimetals'',
Zhongbo Yan, Ren Bi, Huitao Shen, Ling Lu, Shoucheng Zhang, Zhong Wang   +5 more
semanticscholar   +1 more source

Non-Abelian topology of nodal-line rings in PT -symmetric systems [PDF]

Physical review B, 2019
Nodal lines inside the momentum space of three-dimensional crystalline solids are topologically stabilized by a π flux of Berry phase. Nodal-line rings in PT-symmetric systems with negligible spin-orbit coupling (here described as “nodal class AI”) can ...
A. Tiwari, T. Bzdušek
semanticscholar   +1 more source

Enabling Digital Continuity in Virtual Manufacturing for Eco‐Efficiency Assessment of Lightweight Structures by Means of a Domain‐Specific Structural Mechanics Language: Requirements, Idea and Proof of Concept

Advanced Engineering Materials, EarlyView.
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel, Andreas Schuster, Felix Schoenitz, Jean Lefèvre   +3 more
wiley   +1 more source