Results 131 to 140 of about 124,528 (252)

Numerical Fatigue Analysis for Crack Propagation on Ti6Al4V Panel Using XFEM Method

open access: yesMacromolecular Symposia, EarlyView.
ABSTRACT The aim of this work is the validation of a numerical model based on the XFEM method for the prediction of crack propagation in mechanical components subjected to cyclic loads. Through careful bibliographic research, it was decided to take as a case study the analysis of the propagation of a crack passing through a panel in an additive ...
Ciro Coscione   +2 more
wiley   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

open access: yesMed Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo   +8 more
wiley   +1 more source

The cognitive connectome of men and women: a study on sex differences across three cohorts. [PDF]

open access: yesBiol Sex Differ
Gasparre D   +10 more
europepmc   +1 more source

Macroscale Gradient‐Informed Neural Oscillation Topography in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is characterized by large‐scale disruptions in beta and gamma oscillations. Although subcortical beta power is an established biomarker for current adaptive deep brain stimulation (aDBS), it may not fully capture the global pathophysiological burden and the macroscale hierarchical reorganization of the ...
Hao Ding   +8 more
wiley   +1 more source

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