Results 211 to 220 of about 206,767 (279)

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

open access: yesiNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu   +10 more
wiley   +1 more source

Brain network efficiency during social interaction is associated with real-world social network size. [PDF]

open access: yesBehav Brain Funct
Han M   +10 more
europepmc   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

open access: yesiNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen   +6 more
wiley   +1 more source

Stabilised Hyaluronic Acid Gel Rectal Spacers in MRI‐Guided Brachytherapy for Gynaecological Cancers: A Prospective Feasibility Study

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This prospective study investigated the feasibility of stabilised hyaluronic acid gel as a rectal spacer in gynaecological cancer brachytherapy. In twelve patients, the spacer was successfully inserted into the rectovaginal space without serious adverse events, had high visibility on MRI, increased the target‐to‐rectum distance compared with no spacer ...
Carminia Lapuz   +8 more
wiley   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Neoadjuvant chemoimmunotherapy in non-small cell lung cancer: evolving resectability criteria, biomarker-driven postoperative management, and emerging therapeutic strategies. [PDF]

open access: yesJ Immunother Cancer
Patel A   +8 more
europepmc   +1 more source

Intrafraction motion and impact of margin reduction for MR‐Linac online adaptive radiotherapy for pancreatic cancer treatments

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 17-24, March 2025.
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala   +6 more
wiley   +1 more source

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