Results 121 to 130 of about 5,678,918 (297)
NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells
Cell Reports, 2014 Neural induction is the first fundamental step in nervous system formation. During development, a tightly regulated niche modulates transient extracellular signals to influence neural lineage commitment.
Nathan C. Boles +9 more
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Breaking radial symmetry for anterior–posterior axis formation is one of the key developmental steps of vertebrate gastrulation and is established through a succession of transient domains defined by morphology or gene expression. Three such domains were interpreted recently in the rabbit to be part of a “three‐anchor‐point model” for axis ...
Ruben Plöger +2 more
wiley +1 more source
Nodal Parity Invariants of Knotted Rigid Vertex Graphs [PDF]
arXiv, 2012 This paper introduces new invariants of rigid vertex graph embeddings by using non-local combinatorial information that is available at each graphical node. The new non-local information that we use in this paper involves parity in the Gauss code of the underlying graph. We apply these methods to graphs in classical and virtual knot theory, and we give
arxiv
Supplementary Table 1 from MSH3 Protein Expression and Nodal Status in MLH1-Deficient Colorectal Cancers [PDF]
, 2023 Luigi Laghi +10 more
openalex +1 more source
Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials
Exploration, EarlyView.Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu +4 more
wiley +1 more source
Functional study of DAND5 variant in patients with Congenital Heart Disease and laterality defects
BMC Medical Genetics, 2017 Background Perturbations on the Left-Right axis establishment lead to laterality defects, with frequently associated Congenital Heart Diseases (CHDs). Indeed, in the last decade, it has been reported that the etiology of isolated cases of CHDs or cases ...
Fernando Cristo +7 more
doaj +1 more source
Zic2 mutation causes holoprosencephaly via disruption of NODAL signalling.
Human Molecular Genetics, 2016 The ZIC2 transcription factor is one of the genes most commonly mutated in Holoprosencephaly (HPE) probands. Studies in cultured cell lines and mice have shown a loss of ZIC2 function is the pathogenic mechanism but the molecular details of this ZIC2 ...
R. Houtmeyers +8 more
semanticscholar +1 more source
A rare case of colonic adenocarcinoma in a pediatric patient
JPGN Reports, EarlyView.Abstract Lynch syndrome (LS) is an autosomal dominant condition caused by a loss of function in the deoxyribonucleic acid mismatch repair system. This case report presents a 17‐year‐old male with abdominal pain, weight loss, and anemia who was diagnosed with LS‐associated adenocarcinoma of the colon in the setting of a mutS homolog 6 genetic mutation ...
Christine Kaba +4 more
wiley +1 more source
Protein Inference and Protein Quantification: Two Sides of the Same Coin [PDF]
arXiv, 2012 Motivation: In mass spectrometry-based shotgun proteomics, protein quantification and protein identification are two major computational problems. To quantify the protein abundance, a list of proteins must be firstly inferred from the sample. Then the relative or absolute protein abundance is estimated with quantification methods, such as spectral ...
arxiv
PLoS ONE, 2015 Retinol binding proteins (Rbps) are known as carriers for transport and targeting of retinoids to their metabolizing enzymes. Rbps are also reported to function in regulating the homeostatic balance of retinoid metabolism, as their level of retinoid ...
Hao Chen +8 more
doaj +1 more source