Results 141 to 150 of about 5,678,918 (297)
Protein token: a dynamic unit in protein interactions [PDF]
In this study, we introduced a new unit, named "protein token", as a dynamic protein structural unit for protein-protein interactions. Unlike the conventional structural units, protein token is not based on the sequential or spatial arrangement of residues, but comprises remote residues involved in cooperative conformational changes during protein ...
arxiv
Long‐term survival in a dog with suspected primary nodal plasmacytoma treated with surgical excision
Abstract An 8‐year‐old Staffordshire bull terrier presented for left submandibular lymphadenopathy. Cytology showed a monomorphic population of mature plasma cells suggestive of plasma cell neoplasia. On physical examination, no other lymphadenomegaly, cutaneous or oral lesions were found.
Celia Figueroa‐González+4 more
wiley +1 more source
Defect formula for nodal complete intersection threefolds [PDF]
We generalize Werner's defect formula for nodal hypersurfaces in $\mathbb P^{4}$ to the case of a nodal complete intersection threefold.
arxiv
The pathogenesis of peripheral neuropathies in adults is linked to maintenance mechanisms that are not well understood. Here, we elucidate a novel critical maintenance mechanism for Schwann cell (SC)–axon interaction.
Valérie Brügger+18 more
semanticscholar +1 more source
Signaling Centers Drive Brachyury Dynamics and Lineage Commitment in mESC Aggregates
We used a mouse embryonic stem cell aggregate model to compare the use of Chiron and BMP4 signaling as pulses (applied to the whole aggregate) or signaling centers (applied to part of the aggregate). BMP4 as a pulse was shown to drive neural differentiation, with Chiron inhibiting this effect.
A. Rabeling, M. Goolam
wiley +1 more source
Metastasis is the major cause for the high mortality rate of pancreatic cancer. Human embryonic stem cell (hESC) associated genes frequently correlate with malignant disease progression.
Wanxing Duan+13 more
semanticscholar +1 more source
ABSTRACT Background Globally, gastric cancer (GC) ranks as the fourth most deadly and fifth most prevalent kind of cancer. Appropriate treatment methods, precise etiology, and molecular processes of GC are still unclear. Methods In silico and quantitative real‐time reverse transcription polymerase chain reaction (qRT‐PCR)‐based expression of miRNA‐27b ...
Yang Dehuo, Wang Ying, Cao Lin
wiley +1 more source
Tn as a potential predictor for regional lymph node metastasis in T1 colorectal cancer
Background: Approximately 10 percent of T1 colorectal cancer (CRC) has lymph node metastasis. In this study, we aimed to determine possible predictors for nodal involvement in order to aid selection of appropriate patients for organ-preserving strategies.
Li-Jen Kuo+6 more
doaj
Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury
Background Sodium channel (NaCh) expressions change following nerve and inflammatory lesions and this change may contribute to the activation of pain pathways. In a previous study we found a dramatic increase in the size and density of NaCh accumulations,
Johnson Lonnie R+3 more
doaj +1 more source
Nodal regulates bladder cancer cell migration and invasion via the ALK/Smad signaling pathway
Background Bladder cancer is the most common malignant tumor of the urinary tract. We aimed to explore the biological role and molecular mechanism of Nodal in bladder cancer.
Youkong Li+4 more
semanticscholar +1 more source