Results 241 to 250 of about 5,678,918 (297)

A Rare Case of Four Primary Tumors in a Patient With Lynch Syndrome

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT This case emphasizes the complexity of LS and the need for more comprehensive surveillance strategies, particularly in those with MPTs, to enable early detection and improve management.
Mostafa Kamandi, Negin Layegh, Hamideh Feiz Disfani   +2 more
wiley   +1 more source

Prognostic and predictive value of IDO expression in metastatic melanoma treated with Ipilimumab. [PDF]

PLoS One
von Bubnoff D, Schmitt C, Goldinger SM, Schadendorf D, Kähler KC, Hafner C, Kramer N, Fröhlich W, Dummer R, Berking C, Schliep S, Kirchberger MC, Heinzerling L.   +12 more
europepmc   +1 more source

The diagnostic challenges of medullary thyroid carcinoma: A practical guide for cytopathologists

Cancer Cytopathology, Volume 133, Issue 6, June 2025.
Abstract Medullary thyroid carcinoma (MTC) is a rare but potentially aggressive neuroendocrine tumor arising from the thyroid C cells (parafollicular cells) that produce calcitonin, representing 1%–3% of thyroid malignancies but contributing to up to 15% of thyroid cancer‐related deaths.
Marc P. Pusztaszeri, Zahra Maleki
wiley   +1 more source

The Interplay Between Hypocalcemia and Atrioventricular Nodal Blocking Agents in Inducing a Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalemia (BRASH)-Like Phenomenon With Serial Serum Drug Concentrations. [PDF]

Cureus
Inoue F, Okazaki Y, Ichiba T, Chiba T, Namera A.   +4 more
europepmc   +1 more source

Breast cancer in a transgender man

CA: A Cancer Journal for Clinicians, EarlyView.
Alison May Berner, Tristan Michael MacKenzie, Shirish Kulkarni, Chin Chong, Loren Schechter, Caroline Michie, Ole‐Petter Riksfjord Hamnvik   +6 more
wiley   +1 more source

“Tension Chyle Leak”: A Life‐Threatening Sequela of Thoracic Duct Injury Following Resection of BRAF‐Mutated Anaplastic Thyroid Carcinoma

Head &Neck, Volume 47, Issue 6, Page E64-E67, June 2025.
ABSTRACT Background Airway obstruction secondary to chyle leak is an exceptionally rare phenomenon. Here, we describe this complication in a patient with anaplastic thyroid carcinoma (ATC) undergoing consolidative surgery after BRAF‐targeted therapy. Methods A 55‐year‐old man presented with a rapidly enlarging neck mass.
Karim Botros, Khashayar Esfahani, Khalil Sultanem, Jonathan D. Spicer, Alex A. Mlynarek, Michael P. Hier, Marco A. Mascarella   +6 more
wiley   +1 more source

Cortical Surface Spatial Analysis Reveals Altered Brain Functional Network Topology in T2DM With Mild Cognitive Impairment. [PDF]

Brain Behav
Fan Y, Tian J, Yu X, Yang C, Zhang H, Tan J, Zhao Y, Wei J, Huang G, Liu J, Zhao L.   +10 more
europepmc   +1 more source

Induction of SOX17 with stimulation of WNT, TGF‐beta, and FGF signaling drives embryonal carcinomas into the yolk‐sac tumor lineage resulting in increased cisplatin resistance

International Journal of Cancer, Volume 156, Issue 11, Page 2210-2224, 1 June 2025.
What's new? Yolk‐sac tumor formation has been suggested to be an escape mechanism during therapy in patients with relapsing germ cell tumors. The molecular mechanisms inducing yolk‐sac tumor development from stem cell‐like precursor embryonal carcinomas remain unclear.
Mara Kotthoff, Margaretha A. Skowron, Felix Bremmer, Fatma Parmaksiz, Pia Kretschmer, Alexa Stephan, Alexander Fichtner, Tobias Lautwein, Katharina Raba, Janina Fuß, Karl Köhrer, Daniel Nettersheim   +11 more
wiley   +1 more source

Breaking Left-Right Symmetry by the Interplay of Planar Cell Polarity, Calcium Signaling and Cilia. [PDF]

Cells
Shi DL.
europepmc   +1 more source

Native synthetic microbial communities enhance zha‐chili by boosting the fermentation capacity of indigenous microorganisms

iMetaOmics, Volume 2, Issue 2, June 2025.
Traditional fermented foods in synthetic microbial communities (SynComs). We simulated the production of zha‐chili, a traditional fermented food, in the laboratory, intending to address the following questions: How are SynComs constructed, and what is the effect of inoculation with SynComs on the quality of zha‐chilli? How does inoculation with SynComs
Hongye Shen, Chuanyu Du, Shu Jiang, Weiwei Dong, Jinshan Li, Yongmei Hu, Nan Peng, Shumiao Zhao   +7 more
wiley   +1 more source