Results 21 to 30 of about 65,866 (271)

Nodal Signaling Regulates the Bone Morphogenic Protein Pluripotency Pathway in Mouse Embryonic Stem Cells [PDF]

Journal of Biological Chemistry, 2010
Members of the transforming growth factor-β superfamily play essential roles in both the pluripotency and differentiation of embryonic stem (ES) cells. Although bone morphogenic proteins (BMPs) maintain pluripotency of undifferentiated mouse ES cells, the role of autocrine Nodal signaling is less clear.
Katherine E. Galvin, Emily Travis, Della Yee, Terry Magnuson, Jay L. Vivian   +4 more
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Elevated C-reactive protein values predict nodal metastasis in patients with penile cancer [PDF]

BMC Urology, 2013
Abstract Background The nodal status is a strong predictor for cancer specific death in patients with penile carcinoma, and the C-reactive protein (CRP) level at diagnosis has recently been shown to be associated with poor clinical outcome in various solid malignancies.
Andreas Al Ghazal, Sandra Steffens, Julie Steinestel, Rieke Lehmann, Thomas Schnoeller, Anna Schulte-Hostede, Gerd Wegener, Florian Jentzmik, Mark Schrader, Markus A. Kuczyk, Andres Jan Schrader   +10 more
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The significance of autoantibodies against nodal and paranodal proteins in autoimmune nodopathies

Rinsho Shinkeigaku, 2023
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is recognized as a syndrome caused by multiple pathologies. Since the 2010s, it has been clarified that autoantibodies against membranous proteins localized in the nodes of Ranvier and paranodes are positive in subsets of CIDP patients, leading to proposing a new disease concept called ...
Hidenori Ogata
openalex   +4 more sources

Use of Transcriptomic Analyses to Elucidate the Mechanism Governing Nodal Root Development in Eremochloa ophiuroides (Munro) Hack.

Frontiers in Plant Science, 2021
Centipedegrass [Eremochloa ophiuroides (Munro) Hack.] is a perennial warm-season grass that originated in China, and its speed of nodal rooting is important for lawn establishment.
Rui Wang, Haoyan Zhao, Hailin Guo, Junqin Zong, Jianjian Li, Haoran Wang, Jianxiu Liu, Jingjing Wang   +7 more
doaj   +1 more source

Zebrafish Rab5 proteins and a role for Rab5ab in nodal signalling [PDF]

Developmental Biology, 2014
The RAB5 gene family is the best characterised of all human RAB families and is essential for in vitro homotypic fusion of early endosomes. In recent years, the disruption or activation of Rab5 family proteins has been used as a tool to understand growth factor signal transduction in whole animal systems such as Drosophila melanogaster and zebrafish ...
Emma Kenyon, Isabel Campos, James C. Bull, Phoebe Williams, Derek L. Stemple, Matthew D. Clark   +5 more
openalex   +4 more sources

The dynamic right-to-left translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node. [PDF]

PLoS ONE, 2013
The determination of left-right body asymmetry in mouse embryos depends on the interplay of molecules in a highly sensitive structure, the node. Here, we show that the localization of Cerl2 protein does not correlate to its mRNA expression pattern, from ...
José Manuel Inácio, Sara Marques, Tetsuya Nakamura, Kyosuke Shinohara, Chikara Meno, Hiroshi Hamada, José António Belo   +6 more
doaj   +1 more source

Embryonic Protein Nodal Promotes Breast Cancer Vascularization [PDF]

Cancer Research, 2012
Abstract Tumor vascularization is requisite for breast cancer progression, and high microvascular density in tumors is a poor prognostic indicator. Patients bearing breast cancers expressing human embryonic stem cell (hESC)-associated genes similarly exhibit high mortality rates, and the expression of embryonic proteins is associated ...
Daniela F, Quail, Logan A, Walsh, Guihua, Zhang, Scott D, Findlay, Juan, Moreno, Laura, Fung, Amber, Ablack, John D, Lewis, Susan J, Done, David A, Hess, Lynne-Marie, Postovit   +10 more
openaire   +2 more sources

Nodal proteins are target antigens in Guillain‐Barré syndrome [PDF]

Journal of the Peripheral Nervous System, 2012
Neurofascin‐186 (NF186), neuronal cell adhesion molecule (NrCAM), and gliomedin are adhesion molecules playing a central role in the formation of nodes of Ranvier. In Guillain‐Barré syndrome (GBS), immune attack toward the nodes may participate in the disabilities. Autoantibodies to NF186 and gliomedin have been detected in a rat model of GBS. Here, we
Devaux, Jérôme J, Odaka, Masaaki, Yuki, Nobuhiro   +2 more
openaire   +3 more sources

Nodal asymmetry and hedgehog signaling during vertebrate left–right symmetry breaking

Frontiers in Cell and Developmental Biology, 2022
Development of visceral left–right asymmetry in bilateria is based on initial symmetry breaking followed by subsequent asymmetric molecular patterning.
Maria Isabella Negretti, Nina Böse, Natalia Petri, Stanislav Kremnyov, Stanislav Kremnyov, Nikoloz Tsikolia   +5 more
doaj   +1 more source

Advances in the elucidation of nuclear proteins in the model plant Arabidopsis thaliana: based on protein interactions and bioinformatics analysis

Journal of Plant Interactions, 2021
Plant protein–protein interaction (PPI) networks provide valuable information for the understanding of plant biological processes. In this study, we summarized and constructed the nuclear-protein interactome of Arabidopsis based on PPIs, and ...
Fangping Gong, Di Cao, Chengxin Qu, Dongmei Yin, Quanzhi Zhao, Erhui Xiong   +5 more
doaj   +1 more source