Results 51 to 60 of about 65,866 (271)
Protein-O-fucosylation of coreceptors may be required for Nodal signaling in Xenopus
Molecules and CellsNodal-related ligands of TGF-β family play pivotal roles for mesoderm induction and body axis formation during vertebrate early embryogenesis. Nodal ligands are distinct from most other TGF-β ligands family as they require EGF-CFC factors as coreceptors for signaling, in addition to their cognate type I and type II TGF-β receptors. In amphibian Xenopus
Yeon-Jin Kim +3 more
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Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis [PDF]
Brain, 2006 Saltatory conduction in myelinated fibres depends on the specific molecular organization of highly specialized axonal domains at the node of Ranvier, the paranodal and the juxtaparanodal regions. Voltage-gated sodium channels (Na(v)) have been shown to be deployed along the naked demyelinated axon in experimental models of CNS demyelination and in ...
I, Coman +6 more
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Cutaneous Vasculitis: An Unusual Presentation of a Biclonal Nodal Plasma Cell Dyscrasia
Case Reports in Hematology, 2017 We describe an unusual case of a biclonal nodal plasma cell dyscrasia, presenting with a vasculitic rash, end-organ damage, and cytopenias. Serum protein electrophoresis demonstrated a biclonal kappa-restricted paraprotein, with a negative skeletal ...
D. Swan, M. Murphy, E. Elhassadi
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PLoS Genetics, 2011 Vertebrate mesendoderm specification requires the Nodal signaling pathway and its transcriptional effector FoxH1. However, loss of FoxH1 in several species does not reliably cause the full range of loss-of-Nodal phenotypes, indicating that Nodal signals ...
Christopher E Slagle +2 more
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Haematologica, 2018 The molecular biology of primary nodal T- and NK-cell lymphoma and its relationship with extranodal NK/T-cell lymphoma, nasal type is poorly understood. In this study, we assessed the relationship between nodal and extranodal Epstein-Barr virus-positive ...
Siok-Bian Ng +21 more
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Polish Journal of Pathology, 2022 Glypicans (GPC) are involved in the developmental morphogenesis and regulatory processes of cell signalling. Abnormal expression has been observed in different cancer types.
Jaudah Al-Maghrabi +5 more
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The Embryonic Protein Nodal Supports Metastatic Phenotypes in Breast Cancer [PDF]
, 2012 Metastasis is the process by which tumour cells disseminate to distant organ sites. Aberrant expression of stem cell-associated proteins within tumours is associated with metastasis and poor patient prognosis. One example of a stem cell factor that is associated with cancer progression is Nodal, a member of the TGF-β superfamily.
Daniela F. Quail
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Xnrs and activin regulate distinct genes during Xenopus development: activin regulates cell division. [PDF]
PLoS ONE, 2007 BACKGROUND:The mesoderm of the amphibian embryo is formed through an inductive interaction in which vegetal cells of the blastula-staged embryo act on overlying equatorial cells.
Joana M Ramis +2 more
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Polycomb group protein Ezh1 represses Nodal and maintains the left–right axis
Developmental Biology, 2010 The left-right (LR) axis is essential for the proper function of internal organs. In mammals and fish, left-sided Nodal expression governs LR patterning. Here, we show that the Polycomb group protein Ezh1, which is highly conserved from fish to human, participates in LR patterning.
Arai, Daisuke +4 more
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Supplementary Figure 1 from Embryonic Protein Nodal Promotes Breast Cancer Vascularization
, 2023 <p>PDF file - 1.2MB, Nodal antibody used for IHC labels same cells as R&D antibody used in previous studies, but with less non-specific background staining</p>
Lynne-Marie Postovit +10 more
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