Results 61 to 70 of about 65,866 (271)

Supplementary Figure 2 from Embryonic Protein Nodal Promotes Breast Cancer Vascularization

, 2023
<p>PDF file - 1MB, Nodal co-localizes with CD31 in human breast cancer</p>
Lynne-Marie Postovit, David A. Hess, Susan J. Done, John D. Lewis, Amber Ablack, Laura Fung, Juan Moreno, Scott D. Findlay, Guihua Zhang, Logan A. Walsh, Daniela F. Quail   +10 more
openaire   +1 more source

Supplementary Figure 2 from MSH3 Protein Expression and Nodal Status in MLH1-Deficient Colorectal Cancers [PDF]

, 2023
Luigi Laghi, Paolo Bianchi, Gabriele Delconte, Giuseppe Celesti, Giuseppe Di, Monica Pedroni, Anna Maria Chiaravalli, Barbara Jung, Carlo Capella, Maurizio Ponz de Leòn, Alberto Malesci   +10 more
openalex   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Visualisation and quantification of morphogen gradient formation in the zebrafish.

PLoS Biology, 2009
During embryonic development, signalling molecules known as morphogens act in a concentration-dependent manner to provide positional information to responding tissues.
Steven A Harvey, James C Smith
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Aberrant Molecular Myelin Architecture in Charcot-Marie-Tooth Disease Type 1A and Hereditary Neuropathy With Liability to Pressure Palsies. [PDF]

Glia
PMP22 copy number variation disrupts myelin architecture at SLIs and Nodes of Ranvier. Adherens junction and axoglial domain defects are often more severe in CMT1A than HNPP. Findings support PMP22 functioning as a structural organizer of myelin. ABSTRACT Charcot–Marie–Tooth Disease Type 1A (CMT1A) and Hereditary Neuropathy with Liability to Pressure ...
Moss KR, Arowolo MA, Gutierrez DR, Höke A.   +3 more
europepmc   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Tn as a potential predictor for regional lymph node metastasis in T1 colorectal cancer

Asian Journal of Surgery, 2023
Background: Approximately 10 percent of T1 colorectal cancer (CRC) has lymph node metastasis. In this study, we aimed to determine possible predictors for nodal involvement in order to aid selection of appropriate patients for organ-preserving strategies.
Li-Jen Kuo, Chih-Yeu Fang, Ruei-Yu Su, Yen-Kuang Lin, Po-Li Wei, Ching-Huei Kung, Chi-Long Chen   +6 more
doaj   +1 more source

p53 protein expression and its prognostic importance in patients with nodal non-Hodgkin's lymphoma [PDF]

Journal of Korean Medical Science, 2000
To determine whether the p53 expression might be a predictor for treatment response and overall survival in nodal non-Hodgkin's lymphoma (NHL), we analyzed the expression of p53 in 69 NHL patients. p53 protein expression was analyzed by immunohistochemistry with long-term follow up (1-148 months: median 12.2).
M J, Ahn, H, Kim, I S, Kim, J K, Park, M R, Ki, C K, Park   +5 more
openaire   +2 more sources

Diagnostic Utility of Testing for Novel Murine Autoantibodies for Sjögren's Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, Accepted Article.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source