Results 71 to 80 of about 5,678,918 (297)

The Interaction Between Nodal, Hypoxia-Inducible Factor 1 Alpha, and Thrombospondin 1 Promotes Luteolysis in Equine Corpus Luteum

open access: yesFrontiers in Endocrinology, 2019
The regulation of corpus luteus (CL) luteolysis is a complex process involving a myriad of factors. Previously, we have shown the involvement of Nodal in functional luteolysis in mares.
Edyta Walewska   +4 more
doaj   +1 more source

ATF6 as a Nodal Regulator of Proteostasis in the Heart

open access: yesFrontiers in Physiology, 2020
Proteostasis encompasses a homeostatic cellular network in all cells that maintains the integrity of the proteome, which is critical for optimal cellular function. The components of the proteostasis network include protein synthesis, folding, trafficking,
C. Glembotski   +3 more
semanticscholar   +1 more source

Cutaneous Vasculitis: An Unusual Presentation of a Biclonal Nodal Plasma Cell Dyscrasia

open access: yesCase Reports in Hematology, 2017
We describe an unusual case of a biclonal nodal plasma cell dyscrasia, presenting with a vasculitic rash, end-organ damage, and cytopenias. Serum protein electrophoresis demonstrated a biclonal kappa-restricted paraprotein, with a negative skeletal ...
D. Swan, M. Murphy, E. Elhassadi
doaj   +1 more source

Nodal-dependent mesendoderm specification requires the combinatorial activities of FoxH1 and Eomesodermin.

open access: yesPLoS Genetics, 2011
Vertebrate mesendoderm specification requires the Nodal signaling pathway and its transcriptional effector FoxH1. However, loss of FoxH1 in several species does not reliably cause the full range of loss-of-Nodal phenotypes, indicating that Nodal signals ...
Christopher E Slagle   +2 more
doaj   +1 more source

Integration of Nodal and BMP Signaling by Mutual Signaling Effector Antagonism

open access: yesCell Reports, 2020
Summary: Opposing sources of bone morphogenetic protein (BMP) and Nodal signaling molecules are sufficient to induce the formation of a full axis in zebrafish embryos.
Gary Huiming Soh   +2 more
doaj  

Epstein-Barr virus-associated primary nodal T/NK-cell lymphoma shows a distinct molecular signature and copy number changes

open access: yesHaematologica, 2018
The molecular biology of primary nodal T- and NK-cell lymphoma and its relationship with extranodal NK/T-cell lymphoma, nasal type is poorly understood. In this study, we assessed the relationship between nodal and extranodal Epstein-Barr virus-positive ...
Siok-Bian Ng   +21 more
doaj   +1 more source

Xnrs and activin regulate distinct genes during Xenopus development: activin regulates cell division. [PDF]

open access: yesPLoS ONE, 2007
BACKGROUND:The mesoderm of the amphibian embryo is formed through an inductive interaction in which vegetal cells of the blastula-staged embryo act on overlying equatorial cells.
Joana M Ramis   +2 more
doaj   +1 more source

Increased Glypican-3 immunostaining is associated with longer survival outcomes in colorectal carcinoma

open access: yesPolish Journal of Pathology, 2022
Glypicans (GPC) are involved in the developmental morphogenesis and regulatory processes of cell signalling. Abnormal expression has been observed in different cancer types.
Jaudah Al-Maghrabi   +5 more
doaj   +1 more source

Reaction-diffusion models for morphological patterning of hESCs [PDF]

open access: yesarXiv, 2021
In this paper we consider mathematical modeling of the dynamics of self-organized patterning of spatially confined human embryonic stem cells (hESCs) treated with BMP4 (gastruloids) described in recent experimental works. In the first part of the paper we use the activator-inhibitor equations of Gierer and Meinhardt to identify 3 reaction-diffusion ...
arxiv  

Analysis of Prostate Cancer Tumor Microenvironment Identifies Reduced Stromal CD4 Effector T-cell Infiltration in Tumors with Pelvic Nodal Metastasis

open access: yesEuropean Urology Open Science, 2021
Background: Pelvic nodal metastasis in prostate cancer impacts patient outcome negatively. Objective: To explore tumor-infiltrating immune cells as a potential predictive tool for regional lymph node (LN) metastasis. Design, setting, and participants: We
Chara Ntala   +17 more
doaj  

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