Seasonal influenza mRNA vaccine induces stronger innate and comparable or better adaptive responses than licensed inactivated vaccines. [PDF]
Bermúdez-Méndez E +10 more
europepmc +1 more source
T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett +2 more
wiley +1 more source
IL-2 silencing enables Tfh cell expansion during vaccination but is redundant for antibody production. [PDF]
Innocentin S +9 more
europepmc +1 more source
Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm +9 more
wiley +1 more source
Structural and temporal dynamics of pediatric influenza prevention and treatment: a comprehensive bibliometric analysis of historical evolution and emerging trends. [PDF]
Hong J +5 more
europepmc +1 more source
ABSTRACT Valid pre‐clinical animal models are essential for effective drug development in inflammatory skin diseases like atopic dermatitis. Most murine models exhibit low‐to‐moderate inflammatory responses with significant variability, undermining their validity and contributing to high drug attrition rates.
Ida Wang Henriksen +5 more
wiley +1 more source
ABSTRACT Background Genomic surveillance is central to tracking SARS‐CoV‐2 evolution, variant replacement, and transmission dynamics. In Senegal, the Institut Pasteur de Dakar generated one of the largest national longitudinal SARS‐CoV‐2 genomic datasets, offering a unique view of viral spread from the first pandemic wave to the post‐Omicron period ...
Ndeye Awa Ndiaye +21 more
wiley +1 more source
Implications for safety: <i>ASFV-G-ΔI177L</i> vaccine compromises health and semen quality in adult breeding boars. [PDF]
Friedrichs V +8 more
europepmc +1 more source
Combination of adenovirus vector and subunit protein elicits a robust immune response against the SARS-CoV-2 Omicron variant. [PDF]
Ye C +15 more
europepmc +1 more source
Parenteral neonatal priming followed by heterologous mucosal booster favors IgM<sup>+</sup> memory B cell induction over systemic plasma cell differentiation. [PDF]
Foroutan Pajoohian P +7 more
europepmc +1 more source

