Results 71 to 80 of about 30,606 (291)

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Auxotrophy Accounts for Nodulation Defect of Most Sinorhizobium meliloti Mutants in the Branched-Chain Amino Acid Biosynthesis Pathway

Molecular Plant-Microbe Interactions, 2008
Some Sinorhizobium meliloti mutants in genes involved in isoleucine, valine, and leucine biosynthesis were previously described as being unable to induce nodule formation on host plants.
Maria de las Nieves Peltzer, Nicolas Roques, Véréna Poinsot, O. Mario Aguilar, Jacques Batut, Delphine Capela   +5 more
doaj   +1 more source

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes

Advanced Science, EarlyView.
eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu, Yuwei Hu, Xukun Lu, Yuling Cai, Tongtong Li, Ming Gao, Jinlong Ma, Yuan Gao, Shangming Liu, Zi‐Jiang Chen, Jing Meng, Hongbin Liu, Xiaohua Jiang   +12 more
wiley   +1 more source

The relation between root hair infection by Rhizobium and nodulation in Trifolium and Vicia

, 1962
The infection of the root hairs of young seedlings of twelve species of Trifolium and of Vicia hirsuta was examined. The amount of infection (numbers of hairs containing infection threads) at 2 weeks varied much between species of host and was less ...
Nutman, P. S.
core   +1 more source

Search for Nodulation and Nodule Development-related cystatin genes in the genome of Soybean (Glycine max)

Frontiers in Plant Science, 2016
Nodulation, nodule development and senescence directly affects nitrogen fixation efficiency, and previous studies have shown that inhibition of some cysteine proteases delay nodule senescence, so their nature inhibitors, cystatin genes, are very ...
Songli Yuan, Rong Li, Lei Wang, Haifeng Chen, Chanjuan Zhang, Limiao Chen, Qingnan Hao, Zhihui Shan, Xiaojuan Zhang, Shuilian Chen, Zhonglu Yang, Diezhen Qiu, Xinan Zhou   +12 more
doaj   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Soybean CEP6 Signaling Peptides Positively Regulate Nodulation

Agronomy
Nodulation is the most efficient nitrate assimilation system in the ecosystem, while excessive fertilization has an increased nitrate inhibition effect; deciphering the nitrate signal transduction mechanism in the process is of the utmost importance.
Shuai Wu, Xiaoli Wang, Jie Qin, Wenqing Tian, Min Wang, Aiqin Yue, Lixiang Wang, Weijun Du, Jinzhong Zhao   +8 more
doaj   +1 more source

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Phylogeny and Expression of NADPH Oxidases during Symbiotic Nodule Formation

Agriculture, 2018
The mutualistic interaction between gram-negative soil bacteria and the roots of legumes leads to the establishment of nodules, where atmospheric nitrogen is fixed. Nodulation is a multistep process with numerous essential players.
Jesús Montiel, Citlali Fonseca-García, Carmen Quinto   +2 more
doaj   +1 more source

Legume nodulation [PDF]

Current Biology, 2014
SummaryFor reasons that are unclear, no eukaryotic enzymes can break the triple bond of N2. The reduction of N2 to NH3 (nitrogen fixation) is limited to prokaryotes and is catalysed by nitrogenase. Since most of the nitrogen entering the biosphere (around 100 million metric tonnes of N2 per annum) does so through nitrogenase activity (lightning ...
openaire   +2 more sources